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Mastiff puppies and dogs in Lititz, Pennsylvania

Looking for a Mastiff puppy or dog in Lititz, Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Lititz, Pennsylvania

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These Mastiffs are available for adoption close to Lititz, Pennsylvania.
Photo of Mrs.Doubtfire

Mrs.Doubtfire

Mastiff

Female, 3 yrs 9 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Mrs. Doubtfire came to us as a stray, scared and shut down, but each day she’s showing us a little more of her sweet and loving personality! Once she feels comfortable, she starts to let her playful side shine in the yard and happily enjoys affection from her favorite people. We know there’s so much more to discover about this lovely girl as she continues to come out of her shell. Mrs. Doubtfire is looking for a patient, understanding family who will give her the time she needs to feel safe and settle in. In return, you’ll get to watch her blossom into the happy, loving girl she was always meant to be! 3159 Susquehanna Trail N York PA 17406 Kennel #3537
Photo of Bruiser

Bruiser

Mastiff

Male, 5 yrs 2 mos
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Not good with cats, Spayed or Neutered,
Story
He is housebroken and crate trained and does great in a busy household. He was completely calm and quiet during my mom’s 80th birthday party—even with a loud Filipino family gathering and karaoke happening nearby. An 8-year-old autistic family member played with him through the crate, and he was happy and relaxed. He’s getting better on leash and will come back when called if he starts pulling. He may react to some dogs or small animals but is redirectable. He is very people-oriented, loves attention and wants to be near his humans, but will settle when it’s not available. He’s good with kids, probably 6+, because he’s gentle but doesn’t always realize how big he is. With other dogs, he seems more interested in coexisting than wrestling or playing. He needs a dog that respects boundaries and slow introductions are recommended. He’s very food motivated, although chicken may upset his stomach. He isn’t particularly interested in toys or balls. Car rides are his biggest challenge—he tolerates them but gets stressed, drools and doesn’t settle. Overall, he’s a sweet, affectionate, goofy guy who has made great progress and really just wants to be near his people.
Photo of Picasso

Picasso

Mastiff

Male, 1 yr 2 mos
Manchester, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
🎨 Meet Picasso — the happiest little work of art! 👅💙 Picasso is an energetic young boy with a heart of gold and a tongue that has a personality all its own! He came to us with a jaw deformity, which is why his tongue is always sticking out—and honestly, it just makes his adorable face that much more fun. 😍 This sweet boy has a wonderful, kind demeanor and is always ready to enjoy life. He’s still learning all the rules of being a good boy, but he’s eager to learn and doing a great job! 🐾 Picasso is already working on: • Walking nicely on leash • Sit • Come • Down • Learning “okay” as his release word for food • Crate trained Picasso is a mid-to-high-energy boy, so he’d love a family ready to keep him busy, give him plenty of playtime and continue helping him learn. In return, you’ll get a happy, affectionate, goofy boy who is sure to bring plenty of smiles into your life. His tongue may stick out, but so does his personality! 😜 🎨 Picasso is ready to create a masterpiece of a life with his forever family.
Photo of Gamora

Gamora

Mastiff

Female, Puppy
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Please take the time to research the breed before considering fostering/adoption. Because of their immense size, strength, and strong guardian instincts, they are generally not recommended for first-time or novice owners. They require experienced handling, early socialization, and ongoing training throughout their lives. Meet Gamora! Personality: Friendly, funny, all puppy. Favorite Activities: Playing with dogs, playing fetch, going for walks. Medical Issues: None. What would be the best kind of home: An active home that will help keep her well socialized. Need to understand puppies and keep up with training. Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  October 26, 2026, 2:24 pm
Photo of Cosmo

Cosmo

Mastiff

Female, Puppy
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Please take the time to research the breed before considering fostering/adoption. Because of their immense size, strength, and strong guardian instincts, they are generally not recommended for first-time or novice owners. They require experienced handling, early socialization, and ongoing training throughout their lives. Meet Cosmo...an Independent Spirit, Born Guardian Personality: Cosmo is a spirited, adventurous, intelligent Caucasian Shepherd puppy with a big personality and natural guardian instincts. She absolutely loves having an older sister and brother! She has already learned so much from watching them, including manners and how to look after and protect the herd. She is observant, confident, curious, and always ready for her next adventure. This is a working guardian breed, and her protective instincts are already beginning to develop. She needs a family who understands that these traits are part of who she is and is prepared to guide them through consistent training, structure, and responsible socialization. Cosmo is also very independent and already shows the self-assured nature of her breed. She likes to explore, observe, and figure things out for herself. She isn't just looking for someone to entertain her—she has a mind of her own and natural instincts that will need to be guided by someone who understands guardian breeds. Her independence is part of what makes her special, but it also means she'll need a patient, confident owner who can provide consistent boundaries without expecting a people-pleasing dog. Favorite Activities: Running, exploring, playing, and going on wild adventures ALL DAY LONG! Cosmo loves having room to roam, following the animals, observing her surroundings, and learning from the older dogs. She enjoys being involved in everything happening around the homestead and is happiest when she has space to explore and a job to do. She is an energetic puppy who needs plenty of room, stimulation, and appropriate outlets for her natural instincts. A small yard or city lifestyle would not be a good fit for her. Medical Issues: No known medical issues reported at this time. What would be the best kind of home: Cosmo needs an experienced, committed home that understands and respects the Caucasian Shepherd breed. A rural property, farm, or homestead with substantial, secure fencing and plenty of room to roam would be ideal. She is accustomed to being around animals and developing her natural livestock guardian instincts, so a home that understands working guardian dogs would be best. She would benefit from having confident, well-mannered canine companions who can help show her the ropes, although any resident dogs must be a good match for her as she matures. Her new family must be prepared to provide consistent boundaries, structured training, early and ongoing socialization, and responsible management of her developing protective instincts. Food is a serious business for Cosmo! She has already shown resource-guarding tendencies, so her adopters must understand resource guarding and be willing to manage it safely and work on it through appropriate, positive training. She needs careful management around food and other valuable resources, not punishment or confrontational attempts to take things away. Cosmo is adorable, playful, and full of adventure, but she is also growing into a powerful guardian breed with strong instincts. She is not a fit for an apartment, a small city yard, or a home unfamiliar with large livestock guardian breeds. She needs space, knowledgeable handling, and a family willing to help her grow into a confident, stable, well-managed adult dog.Click here to watch a video of Cosmo.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  October 26, 2026, 2:24 pm
Photo of Melvin

Melvin

Mastiff

Male, Young
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Melvin is a young Boerboel mix, estimated to be about 1 year old, who came to us as a stray. We don't know much about his past, but we are excited to help him findthe bright future he deserves. Melvin is a big, goofy boy with an even bigger heart. He absolutely loves other dogs, especially dogs his own size, and nothing makes him happier than a good game of chase or some rough-and-tumble wrestling with a canine friend. Because he's still young, he's full of energy and doesn't always realize just how big he is. One of Melvin's sweetest qualities is how quickly he bonds with his people. He's a true shadow dog who wants to be wherever you are. Whether you're making dinner, watching TV, or working around the house, you will find a big slobbery face following right behind you. He loves being part of the family and is happiest when he's included. Melvin already has a great foundation for his new family. He's house-trained, crate-trained, and walks nicely on a leash, making the transition into his forever home that much easier. He still has plenty to learn, and needs someone who will teach him. He's been around children and has done well, though his size and enthusiastic play style mean he'll do best with a family that can help him continue learning good manners. Melvin is eager to please and will thrive with patient guidance, regular exercise, and lots of opportunities to play. Melvin should not be placed in a home with cats. He simply wants to play with them the same way he plays with big dogs, and because of his size and rough play style, it's just not safe for feline friends. If you're looking for a loyal companion who will stick by your side, make you laugh with his oversized puppy antics, and happily cover you in a little slobber along the way, Melvin may be the perfect fit. He didn't get to choose how his story started, but he's more than ready for a family to help write the rest of it. Click here to watch a video of Melvin.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  October 26, 2026, 2:24 pm

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Mastiff shelters & rescues in Lititz, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Lititz, Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

19.1 miles

York County SPCA

3159 Susquehanna Trail North, York, PA 17406

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

23.8 miles

Koch's Corsos & Rescues

Manchester, PA 17345

Pet Types: dogs

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Rescue

28 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

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Shelter

29.1 miles

Waiting Under the Willow Foundation - PA Transport

Harrisburg, PA 17112

Pet Types: dogs

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Rescue

35.3 miles

Mastiffs to Mutts - Eastern PA

Exton, PA 19341

Pet Types: dogs

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Rescue

48.5 miles

Hinde's Animal Rescue Team

65 S Pennell Road, Media, PA 19063

Pet Types: cats, dogs, farm animals, rabbits, small animals

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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