Great Dane Adoption in Indiana: Great Dane Puppies for Sale in Indiana

Adopt a Great Dane near you in Indiana

Below are our newest added Great Danes available for adoption in Indiana. To see more adoptable Great Danes in Indiana, use the search tool below to enter specific criteria!

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Ronin

Great Dane/Labrador Retriever

Male, 3 yrs

North Vernon, IN

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Story

adoption fees cover spay/neuter, Rabies vaccine, 5 in 1 for dogs, 4 in 1 for cats and a microchip. call for fees or to set up a meet and greet. 812-346-5725

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Rocky

Great Dane

Male, 8 yrs 11 mos

Bloomington, IN

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with cats, House-trained,

Story

**In a foster home; please call 812-349-3492 for more information**Rocky is an extra-large fella who has lived with dogs and cats, likes to lean in for petting and is calm and friendly. He is house trained, low energy and always down for a couch snuggle. Apply to meet this most excellent canine today.

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GD Riley Roo

Great Dane

Male, 9 mos

Mishawaka, IN

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs,

Story

GD Riley Roo was relinquished by no fault of his own. This is a nice boy who is good with other dogs & with people. He is very sweet but would benefit from some basic obedience and confidence building. His birth date is 12/21/25 and he currently weighs 94#.He has been vet. checked, neutered, micro chipped, is up to date on routine shots & wormings including rabies, and has been treated with flea & heart worm preventative per our protocol. He is heart worm & tick born illness negative. His adoption donation is $650 and needs to be cash, certified check, money order or a debit/credit card. There is a 3% processing fee when using a debit/credit card. Please note that any additional funding collected for this pet goes back into our medical acct. to provide for other dogs in need. We do not ship or transport.Please email for an application if you would like to provide this nice kid with his forever home. ##2851557##

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Anna

Great Dane

Female, Adult

Westville, IN

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, House-trained,

Story

Anna is a beautiful Great Dane that was suffering from pyonetra at the shelter and they reached out for help. We were able to get her the emergency vet care that she needed to survive. September 24, 2026, 6:05 pm

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Busch

Great Dane

Male, 1 yr 1 mo

Greensburg, IN

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Not good with kids, House-trained,

Story

This is Busch! Busch is a male Great Dane mix who is 1 year old. He will be fully vetted at the time of a finalized adoption. More about Busch: 💙 likes car rides 💙 potty/crate trained 💙 cannot live with children 💙 timid 💙 eccentric 💙 calm If interested in adopting Busch, please stop by the shelter!‼️Disclaimer: Adoptions are still done on a first come, first serve basis. If multiple inquires come in for the same animal, staff will have the final decision based on the applications received.

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Apollo

Great Dane

Male, Senior

Indianapolis, IN

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Not good with dogs, Good with cats, House-trained,

Story

Looking for a loving home for our sweet boyBorn October 5, 2021, he’s a giant breed senior, but he still acts young and loves going wherever his people go! He’s friendly, affectionate, loves to cuddle, and has been incredibly loved his entire life.He completed a certified training program, knows basic commands, and is leash trained. He has no health concerns aside from seasonal allergies, which are easily managed with Zyrtec. He’s never been crate trained and is happiest lounging beside you or in his orthopedic bed.He’s a wonderful hiking/adventure companion and is very gentle and aware of his size around kids and smaller animals.He has been attacked by other dogs in the past, so he can be nervous around unfamiliar dogs and needs proper introductions. He does not bark or lunge on walks, but he is not dog-friendly while out.He’ll come with his orthopedic bed and supplies.Rehoming is incredibly difficult for us. We love him deeply and want his remaining years to be comfortable.

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Indiana.

Great Dane puppies and dogs in Indiana

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Below are our newest added Great Danes available for adoption in Indiana. To see more adoptable Great Danes in Indiana, use the search tool below to enter specific criteria!

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Great Dane puppies and dogs in Indiana

Jump to:

Adopt a Great Dane near you in Indiana

Below are our newest added Great Danes available for adoption in Indiana. To see more adoptable Great Danes in Indiana, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Indiana cities

Great Dane shelters & rescues in Indiana

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics