Mastiff Adoption in Godfrey, IL: Mastiff Puppies for Sale in Godfrey, IL

Adopt a Mastiff near you in Godfrey, Illinois

These Mastiffs are available in Godfrey, Illinois.

Bella

American Staffordshire Terrier Mastiff

Female, Young

Godfrey, IL

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Spayed or Neutered, Shots are up-to-date,

Story

Hope Rescues is all volunteer, all visits must be scheduled you may do that by filling out an online application as that is needed for a visit. You can find an application our website. Our adoption fee is $275.00 which includes Rabies vaccine, spay/neuter, current heart worm test, DHPP booster, Bordetella vaccine, Microchip, Worming.Bella, Est DOB: 7/8/2025 Female Staffordshire Terrier Mix Meet Bella! Bella is a 7&#226&#128&#145month&#226&#128&#145old Staffordshire Bull Terrier with a whole lot of sparkle in her step. This beautiful pup is bursting with energy, sweetness, and playful charm. She loves fun, loves people, and is always ready for her next adventure. Whether she’s zooming around the yard or snuggling up after a busy day, Bella brings joy everywhere she goes. She’s young, eager to learn, and excited to grow into the amazing companion she’s meant to be. If you’re looking for a lively, loving puppy to join your family, Bella might be the perfect match. Fun. Sweet. Full of life. Bella.Please help us make room to save more homeless pets!!! Adopting from Hope Rescues saves the life of two.. the one you adopt and the one your adoption makes room for. We are a Rescue which means we physically go and save lives. Hope pulls animals on their last day of life from animal control facilities that still use the inhumane gas chamber to put to death homeless pets. Please visit our website at www.hoperescues.orgMarch 16, 2026, 4:00 pm

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Or, how about these Mastiffs in cities near Godfrey, Illinois

These Mastiffs are available for adoption close to Godfrey, Illinois.

Ralph BW

Mastiff Mixed Breed (Large)

Male, 1 yr 3 mos

St Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, Spayed or Neutered,

Story

Ralph the Derp! Ralph is a huge friendly, enthusiastic, uncoordinated 4-legged energetic goofball! He was rescued from “death row” at a high kill shelter, as a skinny stray with a treatable skin condition. His fur has almost completely grown in & he is now at a healthy weight. This overgrown mastiff/Cane Corso mix pup has no comprehension of his size, leaning into humans for affection or trying to ooze onto laps for cuddles. He is being trained not to jump and not to paw for attention/affection/play because he currently has 85# of mass behind those “congenial” moves. Ralph plays well with dogs of all sizes, but would do best with med-to-larger dogs due to his size & poorly curbed gusto. He hordes toys, taking them all to his chosen dog bed of the day. He likes to carry a special toy “baby” in his mouth when going out in the yard. He does need to be fed in his crate & will guard his empty food bowl from other dogs, unless he is distracted with a toy & led outdoors after meals. He is great on a leash, makes awesome grunty sounds when cuddled, enjoys baths. Ralph will make a great addition to an active family with older children. He is eager to please, food and affection oriented (although a bit stubborn at times), making him an ideal candidate for success with continuation of his training. Please consider adopting the gorgeous big derp into your home. Attributes: In training to avoid jumping/pawing Active family He is neutered, microchipped, had recent cherry eye repair and up to date on all vaccines and preventions. Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

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Luke AG

Mastiff American Pit Bull Terrier

Male, 4 yrs 3 mos

St Louis, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,

Story

Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

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Finn AKA Gage JuM

Mastiff Shepherd (Unknown Type)

Male, 7 yrs 2 mos

St Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, Spayed or Neutered,

Story

Finn may look like a rockstar with his striking Mastiff–Shepherd good looks, but at heart, he’s a big, soft lovebug. Weighing in at about 60 pounds, Finn has grown into a handsome boy with a beautiful gray and tan coat, soulful eyes, and an even bigger personality. Despite his star-quality appearance, Finn is more of a laid-back, easygoing guy—think Eeyore vibes, but with engines revved and ready to love. From the moment he wakes up, he’s prepared to shower his people with affection… and trust us, it’s A LOT of love! Finn does well with other dogs and does need a slow, proper introductions to new friends—both two-legged and four-legged. Once he knows you, he loves you deeply. He’s happiest when he has a buddy (human or canine) to share his world with. Affection is Finn’s specialty. When someone comes to greet him, he lights up, runs over with enthusiasm, and hands out slobbery kisses and big hugs like they’re backstage passes. His joy is genuine, his heart is huge, and he’s always thrilled to see his people. If you’re looking for a big, lovable, slightly goofy rockstar who will adore you endlessly, Finn is ready to take center stage in your heart. Local adoption only $200 (in TX)

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Selmar

Mastiff Mixed Breed (Medium)

Male, 2 yrs

St. Louis, MO

Size

(when grown) -

Details

Story

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Meryl Streep

Mastiff Mixed Breed (Medium)

Female, 2 yrs 3 mos

St. Louis, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,

Story

🩷I learned much about adorable Meryl Streep yesterday as we buddied up and attended CARE’S Adoption Event at “Tower Grove Pride” event. This adorable one and a half year-old pup showed her happy self from the moment she jumped in the car and was the perfect backseat rider. 🩷As we walked to CARE’S tent Meryl walked well on the leash. The event was well attended and this sweet pup was friendly and sweet throughout. As participants of all ages came up to say “Hi” and gave her pets she was gentle to everyone. As other dogs passed she was mostly indifferent being content and enjoying the moment. When this precious girl was tired she laid down and fell fast asleep and stayed like that as the action continued all around her. After her short nap we headed back to the car. This precious, perfect girl made the day’s event fun, happy and totally enjoyable for me her sidekick💕 🩷All I could think is this fabulous pup belongs in a loving home and hopefully soon! Meryl Streep, is a treasure and would be a cherished pup for many families. -Her eye condition is called Cherry Eye and is not serious and will be taken care of by CARES clinic when she’s adopted. 🩷She is at CARE STL for you to meet and possibly fall in love just like me🩷🐾XOXO

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Zaffre

Mastiff Mixed Breed (Large)

Male, 5 yrs 5 mos

St. Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, Good with cats, House-trained, Spayed or Neutered,

Story

✨ Meet Zaffre! ✨ Zaffre is a 5-year-old mastiff/pit mix weighing about 85 lbs of pure love and goofiness. He’s been with us for about two weeks, and he has truly been the best house guest. When we met Zaffre at the shelter, he had only been there a couple of days after coming from a neglected situation with 7 other dogs. Despite his rough start, Zaffre has settled into home life beautifully and continues to show just how special he is. 🏡 In the home: • About 90% potty trained (a few marking accidents in our unfinished basement) • Great with our female GSD • Tolerates our two cats • Treat motivated with no signs of food aggression 🐕 Personality & training: Zaffre is a big, goofy lug with the sweetest soul. He’s curious and clearly experiencing many things for the first time, taking it all in with wide-eyed wonder. Because he’s a big boy, he can pull on the leash when he really needs to go, but he responds well to correction and wants to do the right thing. ✂️ Health: Zaffre was neutered last Friday and is recovering very well. Zaffre deserves a loving, patient forever home where he can continue to learn, feel safe, and be cherished. If you’re looking for a loyal companion with a gentle heart and a silly side, Zaffre just might be your perfect match. 💙

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Mastiff puppies and dogs in Godfrey, Illinois

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Adopt a Mastiff near you in Godfrey, Illinois

These Mastiffs are available in Godfrey, Illinois.

Or, how about these Mastiffs in cities near Godfrey, Illinois

These Mastiffs are available for adoption close to Godfrey, Illinois.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Godfrey, Illinois

Mastiff shelters & rescues in Godfrey, Illinois

Looking for a specific shelter or rescue?

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Mastiff basics

Mastiff basics