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Great Dane puppies and dogs in Centennial, Colorado

Looking for a Great Dane puppy or dog in Centennial, Colorado? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Centennial, Colorado

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These Great Danes are available for adoption close to Centennial, Colorado.
Photo of Flower

Flower

Great Dane

Female, 2 yrs 2 mos
Littleton, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Meet Flower aka Daisy!   The name, "Flower," was much too generic for this beautiful and one of a kind gal... Daisy is proof that a little love and a safe place to land can change everything. This beautiful Great Dane entered the shelter system weighing just 53 pounds, but she’s been making an incredible comeback and has gained back so much of the weight she lost. And her personality? Absolutely amazing! Daisy has that classic goofy Great Dane charm. She’s affectionate, fun loving, and gets along wonderfully with dogs of all shapes and sizes. She’s also great with children and is crate trained, making her an all around wonderful companion. She’s got some impressive manners, too! Daisy has a perfect heel and an automatic sit. She’s a smart girl who loves learning and being part of the action. Daisy has come such a long way, and it’s been amazing watching her blossom. She’s got the looks, the personality, the manners, and that big, goofy Dane heart. One thing to know is that Daisy needs some structure and supervision with toys. She tends to think they’re food and may swallow them, so appropriate toys and putting them away when playtime is over are important. Honestly, she’s kind of the perfect dog.  Don't miss out on this one - please complete an application to meet Flower sis Daisy TODAY! Adoption fee includes the following: Spay/Neuter Rabies Vaccination Distemper / Parvo Vaccines (includes series of 3 for puppies) Bordetella Microchip with prepaid lifetime registration Deworming ##2839615##
Photo of Angel

Angel

Great Dane Collie

Female, 8 yrs 9 mos
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Angle is a 4.5 Year Old Great Dane/Smooth Coated Collie Mix. She loves playing with other dogs and ignores cats, unless they want to play. She loves her people and even though she loves playing with other dogs, she really wants her human all to herself. She is also laid back and enjoys a good cuddle and chill on the couch while catching up on some TV. Angle is crate trained, enjoys toys and completely untrustworthy on free roam with high interest items (this includes expensive items; we don’t know how she knows – but she does!) If you think you are Angle's forever home, please complete an adoption application at https://www.savethegiants.com/adoption-process .
Special Needs
Photo of Phryne

Phryne

Great Dane

Female, 4 yrs 8 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs special attention, Spayed or Neutered,
Story
Phryne is named after the heroine in Miss Fisher mysteries. She has a lot to overcome but like her namesake, she’s going to come out on top. She is deaf, she has some health issues, which she’s not old enough for us to fully test yet, and she may have some vision issues. But rest-assured, she doesn't let this stop her. She is the sweetest of hearts and loves to play when it's playtime and snuggle when it's nap time. Phryne is looking for her forever home where she will be loved unconditionally. If you're interested in adopting Phryne, visit savethegiants.com to submit your application. Even if you can't adopt Phryne, you can still support this sweet girl. Check out her Amazon wish list here: https://www.amazon.com/hz/wishlist/ls/15PIZHLSDEAHB
Photo of Cocoa

Cocoa

Great Dane

Female, 8 yrs 11 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Cocoa is looking for her New Forever Home. Cocoa is coming up on 5 years old and is learning the benefits of having fur siblings and toys, lots of toys! She can play a little rough with her fur siblings, but quick to redirect. She has lived with children and seems to ignore cats. Cocoa is an expert at opening sliding gates and sliding doors. She has enough drool for two other dogs. She loves to be in the middle of the action and assumes everyone else wants her there! She is a foodie and likes to sample everyone’s dish! Cocoa’s Back Story: Cocoa is a 5 year old black Great Dane that was owner surrendered to us due to a divorce. Cocoa was just recovering from surgery on her Happy Tail. The skin is so damaged the vet removed the last 2-3” from her tail. If you think Cocoa is your Soulmate - please complete an adoption application at https://www.savethegiants.com/adoption-process .
Photo of Chevy

Chevy

Great Dane

Female, Adult
Lakewood, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
For more information about this Dane, please visit our website at https://rmgreatdane.org. Adoption Applications link can be found on the home page. Meet Chevy   Status: Available Sex: Spayed Female – Gastropexied Color: Merle    Ears: Natural Age: 6 yrs  Weight: 108 lbs Great Dane Experience Required Adoption Fee – has been paid by a generous sponsor   Chevy is a beautiful 6-year-old merle Great Dane looking for a special home that understands her needs and is ready to help her continue building confidence. At her core, Chevy is an incredibly loyal Dane who forms deep bonds with her people. Once she trusts you, she'll happily follow you from room to room, curl up nearby while you relax, and remind you why Great Danes are known for their devotion. She loves playing fetch with her Kong stick, zooming around the yard, and soaking up time with her favorite humans. Chevy is house-trained, crate-trained, knows basic commands including sit, down, come, stay, and off, and responds well to hand signals. She enjoys learning, especially when rewarded with her favorite all-natural treats. While Chevy has many wonderful qualities, she is looking for a very specific home where she can thrive. Chevy can be reactive to people and animals she sees through windows, on walks, or while riding in the car. She will bark and lunge when triggered and will need continued training, patience, and consistent leadership to help her work through these behaviors. Because of her reactivity, Chevy must be the only pet in the home. She is not a candidate for homes with other dogs, cats, or small animals. She also requires an adult-only home with no children. Chevy's ideal adopter will have previous giant breed experience, understand canine body language, and be committed to continuing her training and confidence-building. She would do best in a calm, predictable environment with a securely fenced yard where she can safely run and play. In return, Chevy offers unwavering loyalty, affection, and companionship. She settles in quickly with her people, enjoys spending time with her family, and loves nothing more than being close to the person she trusts. If you're an experienced giant breed owner looking for a devoted companion and are willing to provide the structure and training Chevy needs, she may be the perfect addition to your family. More about Chevy: Great Dane Experience Required Housetrained:Yes Crate trained: Yes Needs a calm home - dog savvy adults and teens only No dogs No cats Reactive to new people and dogs Professional training in process and will need to be continued Fearful and anxious around new people - needs slow introductions   October 26, 2026, 12:20 am
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Photo of Soot

Soot

Great Dane

Male, 2 mos
Sedalia, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
This pup will be available to meet starting on 10/31 They were rescued from a shelter in New Mexico. Meet and greets are by appointment only.  An approved application is required to schedule a meeting. Check out our events page for upcoming open adoption events! We have no additional back story or update for this dog at this time.  When we do, it will be updated here.  This is all the information we have currently. Approved Applicants may make the adoption fee payment by using the link in their approval email.  Partial adoption fees will not hold a dog. If upon meeting the dog of your choosing at your scheduled pickup time you find that you aren't a good match, your deposit will be fully refunded. Adoption fees are non refundable once a pet is taken home.  Adoption fees include vaccines up until time of adoption, microchip, spay/neuter and 1st 30 days of free pet insurance.  We are not affiliated with MetLife pet insurance. (you have to sign up for the insurance or it will not go into effect).  Adoption fees help cover the medical care of the animals while he or she waits for a new home, as well as food and transportation costs. These fees help to provide care for the other animals in the shelter or rescue group who may have medical bills that are much higher than any possible adoption fee. The money also acts as a donation to help support the organization as a whole, allowing the group to continue its efforts to rescue and rehome pets. The dogs in our care are fostered in Colorado, Texas, and New Mexico.  While all dogs are picked up in Colorado, sometimes transport dates change due to unforeseen circumstances delaying pick up. Breed labels are a "best guess" by a shelter veterinarian and cannot be guaranteed.  ##2878208##

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Great Dane shelters & rescues in Centennial, Colorado

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Centennial, Colorado. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

3.4 miles

2 Blondes All Breed Rescue

Littleton, CO 80126

Pet Types: dogs

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Rescue

12.5 miles

Rocky Mountain Great Dane Rescue, Inc

PO Box 280368, Lakewood, CO 80228

Pet Types: dogs

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Rescue

27.3 miles

4 Paws 4 Life Rescue and Boarding

3648 N. Perry Park Road, Sedalia, CO 80135

Pet Types: cats, dogs

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Rescue

33.8 miles

POSO Dog Rescue - Colorado

Boulder, CO 80301

Pet Types: dogs

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Shelter

35.7 miles

Soul Dog Rescue

1245 Factory Circle, Fort Lupton, CO 80621

Pet Types: cats, dogs

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Rescue

35.7 miles

Desiderata Rescue - West Transport

Ft Lupton, CO 80621

Pet Types: cats, dogs

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Rescue

39.8 miles

Hope For Animals-Clear Creek Rescue

POB 63, Georgetown, CO 80444

Pet Types: dogs

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Rescue

44.4 miles

Mile High Canine Rescue, Inc.

Mead, CO 80542

Pet Types: dogs

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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