Mastiff Adoption in Holly, MI: Mastiff Puppies for Sale in Holly, MI

Adopt a Mastiff near you in Holly, Michigan

These Mastiffs are available in Holly, Michigan.

Darcy

Mastiff

Female, Puppy

Holly, MI

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Need to rehome asap . 8 month old pit mastiff rescued from a shelter . Darcy is amazing puppy she doesn’t bark often unless someone comes unannounced at night and it scares her . She’s crate trained and potty trained, I got her for my anxiety but can’t keep her where I’m going she’s truly a great dog she just doesn’t understand her size when it comes to love . She’s a lap dog by heart ❤️ she’s amazing with my four year old . She loves to run and she is great at staying in the yard. With the proper training she would make a great service dog or companion to take everywhere . I’m charging a $50 rehome fee to make sure she goes somewhere and gets loved like she should .

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Or, how about these Mastiffs in cities near Holly, Michigan

These Mastiffs are available for adoption close to Holly, Michigan.

Darcy

Mastiff

Female, Puppy

Holly, MI

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

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Liberty

Mastiff

Female, 2 yrs

Burton, MI

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

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Goose

Mastiff Boxer

Male, 2 yrs 6 mos

Royal Oak, MI

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Spayed or Neutered,

Story

Meet Goose!! Goose is eagerly awaiting life with his forever family! He is the sweetest little Mastiff/Boxer mix you’ll ever meet! He has an estimated birthdate of 1/9/24 and weighs in at a whopping 86 pounds of charm and delight… and he’s currently underweight This super strong boy is great with other dogs and absolutely LOVES people!! Kids are his absolute favorite!! Goose is current on his vaccines but, because he had not been taken care of properly he’s tested positive for heartworms and is being treated for heartworms on slow kill method by The Artemis Project. But don’t let that stop you because the rescue will continue to provide and fund the medications for the duration of his treatment even after he is adopted Bottom line - he is SO ready for a wonderful life with… YOU!!. Please give this beautiful boy a chance to win your heart and become your best friend forever! He is looking for his forever family… that very well may be you! Currently this sweet baby is with our rescue, The Artemis Project, in Arkansas. We DO, however, transport monthly to the metro Detroit area of MI. Because we’re able to transport, we ARE able to accept adoption applications directly from residents of MI. Why do we transport? Because animal overpopulation is severe in our region, and stray and unwanted dogs have very little chance of finding a home here. These babies are, however, at a high risk of being neglected, abused, abandoned, euthanized or even shot (it’s “the way things are done” for some people down here). YOU are truly one of the only safe and happy endings for the lucky ones we are able to rescue. Upon approval of your adoption application, we will then transport your new furbaby to you in the metro Detroit area for just a small travel expense fee of $50 in addition to the adoption fee. MICHIGAN RESIDENTS—>PLEASE CLICK THE LINK BELOW TO FILL OUT THE ADOPTION APPLICATION: https://new.shelterluv.com/form/other/TAP/2450-michigan-adoption Before we can change your new furbaby’s status from "adoptable" to "adoption pending," the $50 transport fee must be paid to secure the adoption. At that time, we will stop accepting applications. The entire adoption fee must be paid prior to the transport in order to ensure your new baby has a spot on the transport. Thank you SO MUCH for giving a homeless Arkansas pup a chance at a real life with a family of their very own!

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Tassels

Mastiff American Staffordshire Terrier

Female, Young

Detroit, MI

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Meet Tassels: A Gentle Giant with a Heart of Gold Introducing Tassels, also lovingly called Mumma by her fosters, a majestic 1.5-year-old Mastiff/Mountain Cur mix whose journey to happiness is truly inspiring. Rescued from a life of uncertainty while extremely pregnant and terrified, Tassels has shown incredible resilience. She was elusive for over a year, only seen on a Ring camera in the Detroit neighborhood she roamed, until we finally secured her safety. Since then, she has blossomed in foster care, watching her babies find their forever homes. Now, it's her turn! Why Tassels is Special: Loving and Affectionate: Tassels expresses her love by placing her massive head in your lap or under your hand for scratches. Her affectionate nature makes her a wonderful companion. Well-Trained and Mannered: She knows basic commands, is potty trained, crate trained, and walks beautifully on a leash. Playful and Joyful: Despite her size, Tassels is playful and enjoys the simple pleasures of cuddling, playing with toys, and lounging in the grass on sunny days. Her zoomies are a sight to behold and bring laughter and joy to everyone around her. Curious and Easygoing: Over the months, Tassels has overcome her initial shyness and now approaches life with curiosity and ease. She’s come to enjoy her interactions with people and her foster sibling. Tassels’ Ideal Home: Tassels would thrive in a home without cats or small dogs. She can live with another dog, but a proper, slow introduction is necessary to ensure a harmonious relationship. Her ideal family will be one that can provide stability, plenty of space for her to stretch her legs, and lots of love. She responds wonderfully to food, affection, and praise, making her a delightful and grateful companion. Is Tassels the Missing Piece in Your Family? If you’re looking for a loyal, loving, and serene companion to add warmth and joy to your home, consider welcoming Tassels into your life. She promises to fill your days with affection and happiness. Ready to adopt Tassels? Apply today! Visit our website to fill out an adoption application and learn more about how you can bring Tassels home! Adoption is $275, which includes spay/neuter at our vet, vaccines, dewormer, microchip, and clean bill of health. Although we work to potty train all of our dogs, we cannot guarantee full house training before adoption. Regression is a normal part of transitioning to a new home and we want our adopters to be prepared for that! APPLY on our WEBSITE: rebeldogsdetroit.com/applytoadopt

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Bubs

Mastiff

Male, Puppy

Belleville, MI

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

You can fill out an adoption application online on our official website.Meet Bubs Born on January 21, 2026, Bubs is an adorable mastiff mix puppy with a whole lot of growing (and cuddling) ahead of him. With his cute black mask and big, clumsy paws, he may have some Cane Corso or Bullmastiff in the mix—but right now, he’s all puppy energy and sweetness. Bubs is incredibly affectionate and loves being close to his people. He’s the kind of pup who will happily follow you around, flop over for belly rubs, and then bounce right back up for playtime. Curious and gentle, he’s still figuring out the world one sniff (and probably one chew) at a time. Like any young pup, he’s learning his manners and building confidence every day. With a little guidance and a lot of love, Bubs is going to grow into a wonderful, loyal companion. For now, he’s just a big baby with a soft heart and an even softer spot for cuddles.Visit this organization's web site to see any additional information available about this pet.July 27, 2026, 9:04 pm

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BAILEY

Mastiff Mixed Breed (Medium)

Female, 6 yrs

Taylor, MI

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Spayed or Neutered, Shots are up-to-date,

Story

Bailey and friend Paisley are with FOCCAS now due to their human having serious health issues. Bailey is used to children and another dog. She enjoys taking walks and would like to be part of a family again.FOCCAS is a foster based, non-profit rescue in Crossville, TN. The adoption fee Includes Age-Appropriate Vaccinations (DA2PPV, Bordetella, Rabies), Deworming, Spay/Neuter, Microchip, Flea/Tick/Heartworm Prevention, and Sheltering. Adult Dogs are Heartworm Tested and Treated as Needed. FOCCAS does not DNA test or guarantee breed. Bailey's adoption fee is $275. If transport is needed, there are additional fees to cover department of agriculture requirements and transport, the additional fee adds $300 to the adoption fee (any location out of Tennessee, East Coast, Great Lakes or New England regions)Thank You for Your Interest in Adopting a Canine Companion from Foccas-tn.org!To Apply Please Copy and Paste to your browser:https://service.sheltermanager.com/asmservice?account=hb2428&method=online_form_html&formid=41LOCATED IN CROSSVILLE, CUMBERLAND COUNTY, TN. WE CAN TRANSPORT OUT OF STATE, Visit out website for a full list of adoptable pets… https://foccas-tn.org/

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Holly, Michigan.

Mastiff puppies and dogs in Holly, Michigan

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Mastiff puppies and dogs in Holly, Michigan

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Adopt a Mastiff near you in Holly, Michigan

These Mastiffs are available in Holly, Michigan.

Or, how about these Mastiffs in cities near Holly, Michigan

These Mastiffs are available for adoption close to Holly, Michigan.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Holly, Michigan

Mastiff shelters & rescues in Holly, Michigan

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics