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Mastiff puppies and dogs in Maryland

Looking for a Mastiff puppy or dog in Maryland? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Maryland

Below are our newest added Mastiffs available for adoption in Maryland. To see more adoptable Mastiffs in Maryland, use the search tool below to enter specific criteria!
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MAX

Mastiff/Cane Corso

Male, 3 yrs
Upper Marlboro, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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Photo of Chloe

Chloe

Mastiff/Great Dane

Female, 8 yrs 1 mo
Ridgely, MD
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
Chloe: 8 Years Old • Great Dane / Mastiff Mix • Approx. 101 lbs • Female • Available in Shelter ⭐ Adoption Fee: $0.00 (generously sponsored) Compatibility & Care Dogs: Previously lived with another dog Cats: Unknown Small Animals: Unknown Children: Yes Energy Level: Low-Medium Best Home: A home that can accommodate a giant breed senior and provide a comfortable pace with opportunities for outdoor activity Medical Needs: Age-related stiffness Special Diet: None 💙 About Chloe "101 pounds of sweetness with a playful side." Meet Chloe, a big, sweet senior girl who may be 8 years old, but she certainly isn't ready to give up all the fun! At 101 pounds, Chloe is an extra-large girl with an equally big personality. She enjoys spending time outside and still has a playful side, especially when there's a big herding ball involved. Watching Chloe chase her ball around the yard is a great reminder that senior dogs can still have plenty of fun. Chloe also enjoys attention from her people and has already shown us that a good booty scratch is one of her favorite forms of affection. She has a lower to moderate energy level and can be a little stiff, especially when getting up from lying down or moving around. Once she's outside, though, Chloe can surprise you with bursts of playfulness and even some running around the yard. Chloe came to the shelter through no fault of her own after previously living with another dog. We are still getting to know her and learning more about what type of home will be the best fit for her. Her history with cats, small animals, and children is currently unknown. If you're looking for a big-hearted senior who enjoys both relaxing with her people and having a little fun outside, Chloe would love to meet you! Chloe's Best Qualities ✔️ Sweet and affectionate ✔️ Loves attention from people ✔️ Enjoys booty scratches ✔️ Still playful despite her age ✔️ Loves chasing a herding ball ✔️ Enjoys time outside ✔️ Lower to moderate energy level ✔️ Big girl with an even bigger personality ⭐ Adoption Fee: $0.00 (generously sponsored) 📍 Come meet Chloe at Caroline County Humane Society 407 W. Belle Street, Ridgely, MD www.carolinehumane.org adoptions@carolinehumane.org 410-820-1600
Photo of Rosie

Rosie

Mastiff/Great Dane

Female, Puppy
Hampstead, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with dogs, Not good with cats, House-trained,
Story
Rosie is a sweet, loving pup looking for the right home where she can feel safe, comfortable, and loved. She came into our lives in February after showing up in a family member’s yard. After several attempts to locate her previous family were unsuccessful, we welcomed her into ours. Rosie is incredibly affectionate with her people and has so much love to give. Unfortunately, she has had conflicts with our other dog that have escalated into fights. During one incident, a family member was accidentally bitten while trying to physically break up the dogs. Because of this history, we believe Rosie would do best as the only dog in a home with an experienced, responsible owner who can provide structure, patience, and lots of love. This is an incredibly difficult decision for our family, and our priority is finding Rosie the right home where she can thrive.
Photo of *DEUCE

*DEUCE

Mastiff/German Shepherd Dog

Male, 1 yr 1 mo
Upper Marlboro, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Meet Deuce! A573603 Deuce is a 1-year-old, 70 lb German Shepherd/Mastiff mix who has been waiting at the shelter since 8/25, after being brought in as a stray. Deuce is just a big, goofy, playful puppy with a healthy bit of young-boy energy! He’s friendly, social, and clearly wants to engage with the world around him. He loves people, although he’s not the type of dog who needs to be glued to your side or sitting in your lap. He seems very interested in treats, too! He’s a handsome young guy with the cutest floppy ears, the most expressive eyes, although he could stand to gain a few pounds.Right now, Deuce is wearing a cone while a small skin wound in his undercarriage area heals.Deuce also seemed very interested in meeting other dogs, although he has not yet had a formal dog-to-dog evaluation. As always, slow introductions after appropriate decompression is recommended. But what has impressed us most about Deuce is how wonderful he has been with children .I’ve personally witnessed two different interactions between Deuce and children under 8, and they showed two different sides of this sweet boy. When one child wanted to play, Deuce was enthusiastic, playful, and friendly. With another little girl, he simply stood calmly beside her while she gently petted him. No jumping all over her, no overwhelming her — just a big dog happily enjoying the attention. For a young, energetic dog who is currently stuck in a stressful shelter environment with very little opportunity to burn off that puppy energy, Deuce is showing some really promising qualities. He has the friendliness, playfulness, and gentleness that could make him an amazing family dog with the right home, structure, exercise, and continued training.Deuce deserves the chance to grow up outside of a kennel and show someone just how special he can be. https://www.instagram.com/reels/DdmKoocsywv/? Please note: The shelter can be a stressful and scary place, and a dog’s behavior here may not fully reflect how they’ll blossom once they feel safe and decompressed at home.Deuce is available for adoption or foster at: Prince George’s County Animal Services3750 Brown Station RdUpper Marlboro, MD 20772
Photo of Diego JuM

Diego JuM

Mastiff/Mixed Breed (Large)

Male, 2 yrs 2 mos
Baltimore, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
I'm Diego, a striking 2-year-old chocolate and blond brindle Mastiff mix, and I've got the heart of an adventurer! 🐕 At 63 pounds of pure energy and loyalty, I'm already neutered and crate trained—ready to be your partner in crime. I thrive with active owners who can match my enthusiasm, and I'm fantastic with other dogs, so playdates are always a go! If you're looking for a friendly, energetic companion who'll stick by your side through thick and thin, come meet me today. 💪❤️ Local adoption fee is $300 (in TX) Out of state adoption fee is $550 (includes transport to your area)
Photo of Jolene

Jolene

Mastiff/Mixed Breed (Large)

Female, 9 yrs 1 mo
Flintstone, MD
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
❤️🐾 MEET JOLENE! 🐾👑 🎶 Jolene, Jolene, Jolene, Joleeeene… I’m begging of you, please "come steal" my man! 🎶 Look at that frosty, magnificent face! Jolene is a gorgeous senior Mastiff who takes Dolly Parton’s warning as a personal goal: she will steal your husband, boyfriend, or dad, and he will completely let her. She’s a sweet, heavy-duty cuddle bug looking for her ultimate retirement home. ❤️ The Jolene Rundown: ✔️ Certified Man-Stealer: Jolene absolutely adores men. If there’s a guy around, she will immediately claim him as her personal lap dog (regardless of her actual size) and best friend. 🐶 Strictly "Only Child" Energy: Jolene must be the only pet in the home. She doesn’t share the spotlight, the couch, or the treats. She’s the Queen, period. 💤Senior Perfection: No crazy puppy chaos here! Her favorite hobbies include sunbathing in the grass, slow-motion walks, and snoring gently next to her favorite guy. Ready to let Jolene steal your heart (and your husband)? She is waiting for a quiet, loving home where she can reign supreme. 📩 Comment below or send us a message to adopt or foster Jolene! www.happygoluckymastiffrescue.com #AdoptASeniorDog #JoleneTheMastiff #GentleGiant #OnlyPet #ManStealer #SeniorDogsRule

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Maryland.

Mastiff puppies and dogs in Maryland cities

Mastiff shelters & rescues in Maryland

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Maryland. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Prince Georges County Animal Services Division

3750 Brown Station Rd., Upper Marlboro , MD 20772

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

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Shelter

Queen Anne's County Animal Services

201 Clay Drive, Queenstown , MD 21658

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Shelter

Caroline County Humane Society

407 West Bell Street, Ridgely , MD 21660

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

RRARS

Hagerstown , MD 21740

Pet Types: dogs

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Rescue

Lucky's Legacy Rescue

Hagerstown , MD 21740

Pet Types: cats, dogs, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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