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Puppies and dogs in Perryville, Missouri

Looking for a puppy or dog in Perryville, Missouri? Adopt a Pet can help you find a new best friend near you.

A pair of dogs

Adopt a dog in Perryville, Missouri

These adorable dogs are available for adoption in Perryville, Missouri. To learn more about each adoptable dog, click on the "i" icon for fast facts, or their photo or name for full details.
Special Needs
Photo of Vedder

Vedder

Mutt

Male, Adult
Sainte Genevieve, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Not good with kids, Good with dogs, Needs special attention, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Vedder was rescued from Home2Home pets as a 10wk old puppy in 2020. We do not know his history before that. He has seizures that are controlled with daily phenobarbitol and allergies that affect his skin that we control with appoquel. He is completely house trained to free roam for numerous hours without any issues. He’s a very smart dog that follows commands and listens well. His problem is he can be territorial when people approach the house and has shown intolerance with kids. He has bit a neighbor kid without being provoked. He 99% has a sweet, loving personality. He can be unpredictable with his behaviors to strangers at times. We do not feel safe with him in the home with a new baby coming.
Photo of O'Reilly

O'Reilly

Feist

Male, Young
Steeleville, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Not good with cats, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. I want A "FUR"ever" HOME!  Read the FULL Bio to see where I am located and contact info:    2026171 Meet O'Reilly! Looking for a sweet boy with a little puppy energy and a softer side? Meet O'Reilly! This handsome 10-month-old, 34-pound neutered male may be a Mountain Feist mix, and he’s ready to find someone who will help him blossom into the amazing dog we know he can be. ❤️ O'Reilly is a little more on the shy side, so he may need some time to feel comfortable and show you his true personality. Once he warms up, he’s a fun-loving young pup who enjoys being around his people. He also does well with other dogs, which can help give him a little extra confidence. Like any young dog, O'Reilly is still working on his potty training and leash skills, so his new family will need to be patient and willing to keep working with him. He has plenty of energy and would love a family ready for walks, playtime, and lots of positive encouragement. 10 months old 34 lbs Neutered male Possible Mountain Feist mix Good with other dogs Not good with cats A little shy at first Lots of puppy energy Working on potty & leash training O'Reilly may not be the first dog to run up and introduce himself, but give this sweet boy a little time and patience, and you just might earn yourself a loyal best friend for life.Visit this organization's web site to see any additional information available about this pet. All ADOPTERS  MUST PLEASE..... ALL Pre-Adopt must be filled out FIRST and  COMPLEATLY to be considered.  ****  Any Incomplete Pre-Adopts will not be considered,  We are Volunteers and our time is very important to us also and we cannot waist it on  incomplete adoption applications.  Please be respectful and sensitive to our time we give to these animals and our mission to save lives. Adoption fees, homechecks, and references are required. ALL of us  at RCHS work very hard to save these precious lives, and our only pay we get as volunteers, is a GOOD HOME LIFE for them, we all are volunteers, so please be patient and considerate of our time and responses. DONATIONS is how we feed and care for them so anything is welcome and or can be made thru PAYPAL Donate Button. Our website is www.randolphhumane.rescuegroups.org or can be mailed to: 5752 State Route 4 Steeleville, IL 62288 (Phone: 618-443-3363) Please leave message if no answer, we will get back with you as soon as we can. August 21, 2026, 7:32 pm
Photo of Diva

Diva

German Shepherd Dog Husky

Female, Young
Steeleville, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats,
Story
You can fill out an adoption application online on our official website. I want A "FUR"ever" HOME!  Read the FULL Bio to see where I am located and contact info:    D2026-169 Meet Diva! Diva is looking for her forever person! At just 11 months old and 48 pounds, Diva is a beautiful German Shepherd/Husky mix with a BIG heart and a personality to match her name! Diva is an incredibly smart, loving, and highly trainable girl. She is what we lovingly call a Velcro dog—if you're moving, she wants to know where you're going! She absolutely loves being glued to your side and soaking up attention from her favorite person. Diva does have some anxieties, so she needs someone who understands that she may need time, patience, consistency, and training while she learns what it means to live in a home. She previously lived outside, so she is not potty trained yet and will need someone willing to teach her the basics of being a house dog. A few things to know about Diva: Learning how to play and interact with other dogs — she needs time to adjust Afraid of cats Not potty trained yet Very smart and highly trainable ❤️ Extremely loving and affectionate Total Velcro girl who wants to be by your side Needs someone committed to helping her build confidence and learn Diva isn't looking for someone who expects her to be perfect on day one. She's looking for someone who will give her a chance, put in the work, and let her blossom at her own pace. With the right person, this gorgeous girl has the potential to be an amazing companion. ❤️ If you're looking for a loyal best friend who will happily follow you everywhere, Diva may be your girl! Visit this organization's web site to see any additional information available about this pet. All ADOPTERS  MUST PLEASE..... ALL Pre-Adopt must be filled out FIRST and  COMPLEATLY to be considered.  ****  Any Incomplete Pre-Adopts will not be considered,  We are Volunteers and our time is very important to us also and we cannot waist it on  incomplete adoption applications.  Please be respectful and sensitive to our time we give to these animals and our mission to save lives. Adoption fees, homechecks, and references are required. ALL of us  at RCHS work very hard to save these precious lives, and our only pay we get as volunteers, is a GOOD HOME LIFE for them, we all are volunteers, so please be patient and considerate of our time and responses. DONATIONS is how we feed and care for them so anything is welcome and or can be made thru PAYPAL Donate Button. Our website is www.randolphhumane.rescuegroups.org or can be mailed to: 5752 State Route 4 Steeleville, IL 62288 (Phone: 618-443-3363) Please leave message if no answer, we will get back with you as soon as we can. August 21, 2026, 7:32 pm
Photo of Napa

Napa

Feist

Male, Young
Steeleville, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Not good with cats, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. I want A "FUR"ever" HOME!  Read the FULL Bio to see where I am located and contact info:    2026172 Meet Napa! Say hello to Napa, a handsome 10-month-old, 38-pound neutered boy who may be a Mountain Feist mix—and boy, does he have some pep in his step! Napa is a fun-loving, energetic young guy who would love an active family ready to keep him busy and help him learn all the important grown-up dog skills. He gets along well with other dogs and would make a great playmate. ❤️ He’s still working on his potty training and leash manners, so his new family will need to be patient and willing to continue his training. He’s young, smart, and ready to learn! 10 months old 38 lbs Neutered male Possible Mountain Feist mix Good with other dogs Not good with cats HIGH energy Working on potty & leash training Napa is ready to find a home where his energy, goofy personality, and puppy antics will be appreciated. If you're looking for a fun adventure buddy who will keep you on your toes, Napa might just be your guy! Come meet Napa and let him add a little excitement to your life! ❤️Visit this organization's web site to see any additional information available about this pet. All ADOPTERS  MUST PLEASE..... ALL Pre-Adopt must be filled out FIRST and  COMPLEATLY to be considered.  ****  Any Incomplete Pre-Adopts will not be considered,  We are Volunteers and our time is very important to us also and we cannot waist it on  incomplete adoption applications.  Please be respectful and sensitive to our time we give to these animals and our mission to save lives. Adoption fees, homechecks, and references are required. ALL of us  at RCHS work very hard to save these precious lives, and our only pay we get as volunteers, is a GOOD HOME LIFE for them, we all are volunteers, so please be patient and considerate of our time and responses. DONATIONS is how we feed and care for them so anything is welcome and or can be made thru PAYPAL Donate Button. Our website is www.randolphhumane.rescuegroups.org or can be mailed to: 5752 State Route 4 Steeleville, IL 62288 (Phone: 618-443-3363) Please leave message if no answer, we will get back with you as soon as we can. August 21, 2026, 7:32 pm
Photo of Trixie

Trixie

Jack Russell Terrier Chihuahua

Female, Adult
Steeleville, IL
Size
(when grown) Small 25 lbs (11 kg) or less
Details
Good with dogs, Good with cats, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. I want A "FUR"ever" HOME!  Read the FULL Bio to see where I am located and contact info:    D2026-151     Meet Trixie! Looking for a tiny dog with a big personality? Meet Trixie, a 5-year-old Jack Russell Terrier/Chihuahua mix who packs a whole lot of charm into her 13-pound frame! Trixie is convinced she's much bigger than she actually is, but don't let her tiny size fool you—this little lady's favorite job is loving her people. She gets along great with other dogs, cats, and children, so she's happy to make friends wherever she goes. She's a clean roommate who keeps her kennel tidy, walks nicely on a leash, and knows a few basic commands... when she decides they're worth listening to. (We're calling it "selective hearing," and she's sticking to that story.) Whether she's supervising your daily activities, claiming the best spot on the couch, or making sure you never have to use the bathroom alone again, Trixie is always ready to brighten your day with her sweet personality and endless affection. If you're looking for a loyal sidekick, a professional cuddle buddy, and a tiny comedian all rolled into one adorable package, Trixie is ready to move in and run your house—er, fill your heart!Visit this organization's web site to see any additional information available about this pet. All ADOPTERS  MUST PLEASE..... ALL Pre-Adopt must be filled out FIRST and  COMPLEATLY to be considered.  ****  Any Incomplete Pre-Adopts will not be considered,  We are Volunteers and our time is very important to us also and we cannot waist it on  incomplete adoption applications.  Please be respectful and sensitive to our time we give to these animals and our mission to save lives. Adoption fees, homechecks, and references are required. ALL of us  at RCHS work very hard to save these precious lives, and our only pay we get as volunteers, is a GOOD HOME LIFE for them, we all are volunteers, so please be patient and considerate of our time and responses. DONATIONS is how we feed and care for them so anything is welcome and or can be made thru PAYPAL Donate Button. Our website is www.randolphhumane.rescuegroups.org or can be mailed to: 5752 State Route 4 Steeleville, IL 62288 (Phone: 618-443-3363) Please leave message if no answer, we will get back with you as soon as we can. August 21, 2026, 7:32 pm
Photo of Tramp

Tramp

Terrier (Unknown Type, Medium)

Male, Senior
Steeleville, IL
Size
(when grown) Small 25 lbs (11 kg) or less
Details
Good with dogs, Good with cats, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. I want A "FUR"ever" HOME!  Read the FULL Bio to see where I am located and contact info:    D2026-139.      Tramp is ready for adoption! He went to the veterinarian for a good teeth cleaning and some vetting and is ready! This poor senior has been through so much. He has hair growing back in the patches he was missing from flea allergies. Tramp is said to be around 9 years old and 17 pounds.  When he first came to us he was scared as can be but he’s come out of his shell and turned into such a lover. He is the type to curl into your lap and go to sleep! He does well for car rides and snuggles into his bed. Interested in meeting him?Visit this organization's web site to see any additional information available about this pet. All ADOPTERS  MUST PLEASE..... ALL Pre-Adopt must be filled out FIRST and  COMPLEATLY to be considered.  ****  Any Incomplete Pre-Adopts will not be considered,  We are Volunteers and our time is very important to us also and we cannot waist it on  incomplete adoption applications.  Please be respectful and sensitive to our time we give to these animals and our mission to save lives. Adoption fees, homechecks, and references are required. ALL of us  at RCHS work very hard to save these precious lives, and our only pay we get as volunteers, is a GOOD HOME LIFE for them, we all are volunteers, so please be patient and considerate of our time and responses. DONATIONS is how we feed and care for them so anything is welcome and or can be made thru PAYPAL Donate Button. Our website is www.randolphhumane.rescuegroups.org or can be mailed to: 5752 State Route 4 Steeleville, IL 62288 (Phone: 618-443-3363) Please leave message if no answer, we will get back with you as soon as we can. August 21, 2026, 7:32 pm

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Dog shelters and rescues in Perryville, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for dogs in Perryville, Missouri. Browse these rescues and shelters below.

Here are a few organizations closest to you:

Shelter

Randolph County Humane Society

5752 State Route 4, Steeleville, IL 62288

Pet Types: cats, dogs

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Rescue

Yorkie Haven Rescue - MO

Fredericktown, MO 63645

Pet Types: dogs

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Safe Harbor Animal Sanctuary

359 Cree Lane, Jackson, MO 63755

Pet Types: cats, dogs

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Rescue

Mac’s Mission

Jackson, MO 63755

Pet Types: dogs, reptiles

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Rescue

United Yorkie Rescue - IL- Ava

Ava, IL 62907

Pet Types: dogs

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Hospets

Marble Hill, MO 63764

Pet Types: dogs

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Rescue

Adopt Today!

Farmington, MO 63640

Pet Types: cats, dogs

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Shelter

Farmington Pet Adoption Center

2901 Highway 67 South, P.O. Box 45, Farmington, MO 63640

Pet Types: cats, dogs

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Rescue

Love A Dog Rescue and Sanctuary

2611 Hwy Oo, Farmingtoon, MO 63640

Pet Types: dogs

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Shelter

Humane Society of Southern Illinois

95 Humane Road, Murphysboro, IL 62966

Pet Types: cats, dogs

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For a comprehensive list of all shelters and rescues, try our search page. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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