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Mastiff puppies and dogs in Manhattan, Illinois

Looking for a Mastiff puppy or dog in Manhattan, Illinois? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Manhattan, Illinois

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Manhattan, Illinois

These Mastiffs are available for adoption close to Manhattan, Illinois.
We'll also keep you updated on Duke's adoption status with email updates.
Photo of Duke

Duke

Mastiff

Male, Adult
Crete, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Meet Duke! A two year old Mastiff mix that is looking for his forever family. In the home he is house broken, crate trained, and loves to be with his humans. As an XL breed dog, he could still use some reinforcement of basic manners. He's very strong on leash and tends to jump and get a little mouthy when he plays or gets excited. A family with large breed experience that is willing to invest some time and energy into basic training would be ideal. Another requirement would be no children under 10. Outside the home, Duke is a tad insecure and can be slightly reactive to new dogs. After a quick introduction, however, he does great (especially with female dogs). He can, however, tend to get too excited and possessive over toys so a family that can maintain boundaries in their home would be required. As for cats... this big boy LOVES them and would have no problem sharing his space with a dog savvy feline. If you are interested in Duke please fill out an adoption application at: https://www.dogsaredeservingrescue.com/adoptable-dogs/adoption-application/November 12, 2025, 1:26 pm
We'll also keep you updated on Mac's adoption status with email updates.
Photo of Mac

Mac

Mastiff American Pit Bull Terrier

Male, 7 yrs 3 mos
Naperville, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hi, All Mac, here short for Mac truck lol. If you love big goofy dogs, I'm your guy. I am 100 lbs. of cuddle bug. I really don't think I am as big as they say I am because I would prefer to just be a couch Potatoe and lay next to my people and chew on a bone. I am a people kind of guy and love everyone I meet. I can probably live with another dog, but he would have to be calmer like me. but little dogs and very young children I would be afraid of because I am clumsy and wouldn't want to hurt them. I definitely don't think I could handle cats. But I know a lot of commands they say I am really smart and a fast learner. I am potty trained but do not like cages. I am strong on a leash so I would need a strong owner. Fill out an app here. https://docs.google.com/forms/d/e/1FAIpQLSdsHBf5NUtvyBYpzWm6Z5Z0JosLBTsDC98oxPTfxtM9brrc7Q/viewform
We'll also keep you updated on DJ's adoption status with email updates.
Photo of DJ

DJ

English Mastiff

Male, 3 mos
Naperville, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
If you want to add a little unconditional love to your life...I am right here!! I’m an active, fun loving and sweet 2 month old English Mastiff X lil boy. I am in search of my forever family and home that will love me and make endless memories with me. I am the missing piece to completing your wonderful family. Investing your love into me will be so worth it!! I am good with children and other dogs. I was rescued when my family decided that they needed help placing us in our forever homes. Please add a lotta unconditional love, sloppy kisses, tail wags and endless happiness to your family and contact adoptions@wagginghearts.org for an adoption application and bring me home. I will come with the works (Neutered, up to date on everything, micro chipped, fecal, heart worm tested if age appropriate, heartworm, flea and tick prevented, a free vet visit and medical insurance). What more could a new family ask for? Love and Kisses, DJ
We'll also keep you updated on Ocean's adoption status with email updates.
Photo of Ocean

Ocean

English Mastiff

Female, 1 yr 7 mos
Oswego, IL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Hi, I’m Ocean and I’m new to the rescue. I am currently decompressing and getting used to my foster family. Check back as my foster family learns more about me! Dog’s Name: Ocean  Location: Waunakee, WI Date of Birth: 6/1/2024 Gender: Female Breed: Cane Corso Color: Brindle Dog's Weight: 83 Gets along with: Dogs?: Unknown  Cats?:  All Cats  Kids?: Older kids Training: Leash trained: Pulls on leash, but walks nicely with a harness Crate/Kennel:  Doesn't want to go into her crate, but settles nicely once in. Potty trained: Indicates a need to potty and doesn’t have indoor accidents Car: Rides well in car - needs to be tethered Meet Ocean! Ocean is a sweet, affectionate girl with a big heart and an even bigger personality. She loves people and shows her excitement with enthusiasm—sometimes a little too much, which is part of her charm! Ocean will benefit from continued training, especially with leash manners, as she is strong and can jump when she gets excited. Because of her strength and energy, an adopter with prior dog experience would be ideal. While she is a giant breed, specific giant-breed experience isn’t required—just a willingness to work with her, set boundaries, and help her polish her manners. With consistency, positive reinforcement, and a home ready to guide her, Ocean has all the potential to become a wonderful, well-mannered companion. She’s ready to bring lots of love, joy, and a little splash of fun to the right home! Until the profile is removed from the public’s view, this dog is considered available for adoption. To apply to adopt from Just Giants Rescue fill out an online. All approved applications are good for 12 months. Meet and greets can be scheduled with approved adopters. All dogs adopted from Just Giants Rescue are up to date on vaccines (Rabies, DHPP, Bordetella), microchipped, and spayed or neutered. Some exceptions may apply. All adoption fees are non-refundable; Just Giants is a NFP 501(c)3 organization. Meet and greets can be scheduled with approved adopters. Transportation from the foster home to the adopter is the responsibility of the adopter to coordinate. Just Giants does not adopt outside of the continental US. To apply to adopt from Just Giants Rescue, you can visit https://justgiants.org/adopt/ to fill out an application. All dogs adopted from Just Giants Rescue are up to date on shots, microchipped, and spayed or neutered. Some exceptions may apply. For more information about Just Giants or the dogs we rescue, please visit justgiants.org. All puppies will be adopted with age-appropriate vaccines and a spay/neuter contract. Adoption Fees $750 - 12 months or younger; $150 snip it ticket  $600 - 1 to 3 years old $500 - 4 to 6 years old $300 - 7+ years old; includes senior blood panel ##2634528##
We'll also keep you updated on Waylon's adoption status with email updates.
Photo of Waylon

Waylon

Mastiff

Male
Oswego, IL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Shots are up-to-date,
Story
Hi, I’m Waylon and I am gaining weight still. Check back as my foster family learns more about me and helps me heal! Dog’s Name: Waylon Location: Seneca, MO Age or Date of Birth: Gender: Male Breed:Mastiff Color: Fawn Dog's Weight: 54 Gets along with: Dogs?: Unknown Cats?:  Unknown Kids?: All kids Training: Leash trained: working on it Crate/Kennel:  working on it Potty trained: working on it Car:  working on it Meet Waylon Waylon is new to the rescue world. Right now, he's doing something very important — learning that he is safe.   Everything is still a bit scary and unfamiliar, so he's taking his time to decompress and get used to his foster family and new surroundings. He's a very timid and unsure soul, but with patience, kindness, and gentle reassurance, he is slowly starting to settle in. His foster family is giving him the space he needs. As he continues to adjust, his personality will start to shine through. Please check back soon as his foster family learns more about him and shares updates on his progress. Waylon will do best with a calm, patient adopter who understands that trust takes time — but the reward of watching a scared dog learn to feel safe is truly something special. If you believe in second chances and quiet victories, Waylon might just be the perfect boy for you. Until the profile is removed from the public’s view, this dog is considered available for adoption. To apply to adopt from Just Giants Rescue fill out an online. All approved applications are good for 12 months. Meet and greets can be scheduled with approved adopters. All dogs adopted from Just Giants Rescue are up to date on vaccines (Rabies, DHPP, Bordetella), microchipped, and spayed or neutered. Some exceptions may apply. All adoption fees are non-refundable; Just Giants is a NFP 501(c)3 organization. Meet and greets can be scheduled with approved adopters. Transportation from the foster home to the adopter is the responsibility of the adopter to coordinate. Just Giants does not adopt outside of the continental US. To apply to adopt from Just Giants Rescue, you can visit https://justgiants.org/adopt/ to fill out an application. All dogs adopted from Just Giants Rescue are up to date on shots, microchipped, and spayed or neutered. Some exceptions may apply. For more information about Just Giants or the dogs we rescue, please visit justgiants.org. All puppies will be adopted with age-appropriate vaccines and a spay/neuter contract. Adoption Fees $750 - 12 months or younger; $150 snip it ticket  $600 - 1 to 3 years old $500 - 4 to 6 years old $300 - 7+ years old; includes senior blood panel ##2630272##
We'll also keep you updated on Tiger's adoption status with email updates.
Photo of Tiger

Tiger

Mastiff Belgian Malinois

Male, 1 yr 2 mos
Naperville, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Meet Tiger – The Confident Leader with a Heart of Gold!  Tiger is ready to lead his way into your heart! Born on 10/26/24, this sweet Mastiff and Malinois mix is a natural leader —confident and curious. But don’t let his strong presence fool you—he’s also incredibly lovable, affectionate, and eager to bond with his humans. Tiger is a well-rounded boy who enjoys both playtime and cuddles. He’s been well-socialized and is potty trained, making him a great addition to a loving home. Whether he’s leading the charge on a new adventure or snuggling up for some quality time, Tiger is the perfect balance of strength and sweetness. Up to date on vaccines  Confident, affectionate, and a great companion Crate trained and potty trained  Professionally trained in basics (sit, stay, walking on leash, etc) Foster-to-adopt option available If you’re looking for a brave, smart, and loving boy to be your loyal companion, Tiger is your perfect match! Apply to adopt or foster today—don’t forget to mention Tiger’s name! ##2313590##

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Related breeds in Manhattan, Illinois

Mastiff shelters & rescues in Manhattan, Illinois

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Manhattan, Illinois. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

20.2 miles

Dogs are Deserving

Crete, IL 60417

Pet Types: dogs

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Rescue

22.1 miles

Wagging Hearts - Naperville

1552 South Rt 59, PO Box #1487, Naperville, IL 60564

Pet Types: cats, birds, dogs

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Rescue

22.1 miles

Find A Home Pet Rescue, Inc

Naperville, IL 60564

Pet Types: cats, dogs

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Rescue

23.5 miles

Just Giant Rescue Inc - Illinois Chapter

PO Box 358, Oswego, IL 60543

Pet Types: dogs

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Rescue

24.9 miles

Angel Dog Alliance

Naperville, IL 60540

Pet Types: dogs

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Rescue

26.4 miles

Lucky Tails Rescue - IL transport

211 Pine Branch Drive, chicago, IL 60638

Pet Types: dogs

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Rescue

26.5 miles

Jellystone Bark's Rescue Rangers

Yorkville, IL 60560

Pet Types: dogs

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Rescue

36.7 miles

Focus on Cumberland County Animal Safety-IL Transport Stop

Chicago, IL 60176

Pet Types: cats, dogs

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Rescue

39.6 miles

God's Dogs Rescue of TX for IL Transport Stop

Rosemont, IL 60018

Pet Types: dogs

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Shelter

43.4 miles

Wright-Way Rescue

5915 Lincoln Ave, Morton Grove, IL 60053

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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