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Mastiff puppies and dogs in Manhattan, Illinois

Looking for a Mastiff puppy or dog in Manhattan, Illinois? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Manhattan, Illinois

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Manhattan, Illinois

These Mastiffs are available for adoption close to Manhattan, Illinois.
We'll also keep you updated on Josie's adoption status with email updates.
Photo of Josie

Josie

Mastiff Mixed Breed (Medium)

Female, 3 mos
Homewood, IL
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
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We'll also keep you updated on Dobbie's adoption status with email updates.
Photo of Dobbie

Dobbie

Mastiff Mixed Breed (Medium)

Male, 3 mos
Homewood, IL
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
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We'll also keep you updated on Duke's adoption status with email updates.
Photo of Duke

Duke

Mastiff

Male, Adult
Crete, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Meet Duke! A 3 year old Mastiff mix that is looking for his forever family. In the home he is house broken, crate trained, and loves to be with his humans. He's very strong on leash and tends to jump and get a little mouthy when he plays or gets excited. A requirement would be no children under 10. He can, however, tend to get too excited and possessive over toys so a family that can maintain boundaries in their home would be required. As for cats... this big boy LOVES them and would have no problem sharing his space with a dog.       If you are interested in Duke please fill out an adoption application at: https://www.dogsaredeservingrescue.com/adoptable-dogs/adoption-application/March 5, 2026, 12:22 pm
We'll also keep you updated on Mac's adoption status with email updates.
Photo of Mac

Mac

Mastiff American Pit Bull Terrier

Male, 7 yrs 5 mos
Naperville, IL
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hi, All Mac, here short for Mac truck lol. If you love big goofy dogs, I'm your guy. I am 100 lbs. of cuddle bug. I really don't think I am as big as they say I am because I would prefer to just be a couch Potatoe and lay next to my people and chew on a bone. I am a people kind of guy and love everyone I meet. I can probably live with another dog, but he would have to be calmer like me. but little dogs and very young children I would be afraid of because I am clumsy and wouldn't want to hurt them. I definitely don't think I could handle cats. But I know a lot of commands they say I am really smart and a fast learner. I am potty trained but do not like cages. I am strong on a leash so I would need a strong owner. Fill out an app here. https://docs.google.com/forms/d/e/1FAIpQLSdsHBf5NUtvyBYpzWm6Z5Z0JosLBTsDC98oxPTfxtM9brrc7Q/viewform
We'll also keep you updated on Brigid's adoption status with email updates.
Photo of Brigid

Brigid

Mastiff

Female
Oswego, IL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
Hi, I’m Brigid and I’m new to the rescue. I am currently decompressing and getting used to my foster family. Check back as my foster family learns more about me! Dog’s Name:  Brigid Location:  Mundelein, IL Date of Birth: Gender:  Female Breed: Mastiff Color: Brindle Dog's Weight: Until the profile is removed from the public’s view, this dog is considered available for adoption. To apply to adopt from Just Giants Rescue fill out an online. All approved applications are good for 12 months. Meet and greets can be scheduled with approved adopters. All dogs adopted from Just Giants Rescue are up to date on vaccines (Rabies, DHPP, Bordetella), microchipped, and spayed or neutered. Some exceptions may apply. All adoption fees are non-refundable; Just Giants is a NFP 501(c)3 organization. Meet and greets can be scheduled with approved adopters. Transportation from the foster home to the adopter is the responsibility of the adopter to coordinate. Just Giants does not adopt outside of the continental US. To apply to adopt from Just Giants Rescue, you can visit https://justgiants.org/adopt/ to fill out an application. All dogs adopted from Just Giants Rescue are up to date on shots, microchipped, and spayed or neutered. Some exceptions may apply. For more information about Just Giants or the dogs we rescue, please visit justgiants.org. All puppies will be adopted with age-appropriate vaccines and a spay/neuter contract. Adoption Fees $750 - 12 months or younger; $150 snip it ticket  $600 - 1 to 3 years old $500 - 4 to 6 years old $300 - 7+ years old; includes senior blood panel ##2676531##
We'll also keep you updated on Orville's adoption status with email updates.
Photo of Orville

Orville

Mastiff

Male, 8 yrs 8 mos
Oswego, IL
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hi, I’m Orville.  I'm on a medical hold while I receive some needed treatment.  Soon I'll be ready for my forever home so please click adopt to get your application approved. Dog’s Name: Orville Location: St. Joseph, IL Date of Birth: 06/28/2017 Gender: Male Breed: Mastiff Mix Color: Brindle Dog's Weight: 118 Gets along with: Dogs?: All Dogs Cats?:  All Cats Kids?: Have not tested with kids Training: Leash trained: Walks loose on leash Crate/Kennel:  Goes into crate/kennel on command Potty trained: Indicates a need to potty and doesn’t have indoor accidents Car:  Rides Well in car Meet Orville Orville is the definition of laid-back love.This tall, gentle boy is happiest right by your side — truly your shadow in the very best way. Whether you're moving from room to room or enjoying a quiet afternoon, Orville will calmly stroll along beside you. He’s a pleasure on walks and just as easy in the yard, where he prefers to stay close rather than wander. Orville is wonderfully quiet and only speaks up when it’s time to head outside. His house manners are impeccable — he has his potty routine down perfectly and hasn’t had a single accident in foster care. He politely sits for his food bowl and treats, and at this stage in life, he’s more about companionship than chaos. While he may be a little slower these days, that just makes him an easy keeper and an incredibly devoted companion. Orville is quiet and well mannered, great on walks, fully house trained, does not require a fenced yard, will do well as an only dog or with a calm buddy, and an excellent choice for a first-time giant breed owner. Orville isn’t looking for adventure — he’s looking for connection. If you’re hoping for a steady, gentle presence who will faithfully follow you through life’s simple moments, Orville is ready to be your loyal best friend. Until the profile is removed from the public’s view, this dog is considered available for adoption. To apply to adopt from Just Giants Rescue fill out an online. All approved applications are good for 12 months. Meet and greets can be scheduled with approved adopters. All dogs adopted from Just Giants Rescue are up to date on vaccines (Rabies, DHPP, Bordetella), microchipped, and spayed or neutered. Some exceptions may apply. All adoption fees are non-refundable; Just Giants is a NFP 501(c)3 organization. Meet and greets can be scheduled with approved adopters. Transportation from the foster home to the adopter is the responsibility of the adopter to coordinate. Just Giants does not adopt outside of the continental US. To apply to adopt from Just Giants Rescue, you can visit https://justgiants.org/adopt/ to fill out an application. All dogs adopted from Just Giants Rescue are up to date on shots, microchipped, and spayed or neutered. Some exceptions may apply. For more information about Just Giants or the dogs we rescue, please visit justgiants.org. All puppies will be adopted with age-appropriate vaccines and a spay/neuter contract. Adoption Fees -  $750 - 12 months or younger; $150 snip it ticket  $600 - 1 to 3 years old $500 - 4 to 6 years old $300 - 7+ years old; includes senior blood panel ##2653868##

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Manhattan, Illinois.

Mastiff puppies and dogs in nearby cities

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Related breeds in Manhattan, Illinois

Mastiff shelters & rescues in Manhattan, Illinois

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Manhattan, Illinois. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

18.2 miles

Fido's Landing

Homewood, IL 60430

Pet Types: dogs

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Rescue

20.2 miles

Dogs are Deserving

Crete, IL 60417

Pet Types: dogs

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Rescue

22.1 miles

Find A Home Pet Rescue, Inc

Naperville, IL 60564

Pet Types: cats, dogs

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Rescue

23.5 miles

Just Giant Rescue Inc - Illinois Chapter

PO Box 358, Oswego, IL 60543

Pet Types: dogs

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Rescue

24.9 miles

Angel Dog Alliance

Naperville, IL 60540

Pet Types: dogs

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Rescue

26.4 miles

Lucky Tails Rescue - IL transport

211 Pine Branch Drive, chicago, IL 60638

Pet Types: dogs

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Rescue

33.2 miles

4 Paws 4 U 4 Ever

West Chicago, IL 60185

Pet Types: dogs

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Rescue

35.2 miles

Big Dogs Don't Cry

Merrilliville, IN 46410

Pet Types: cats, dogs

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Rescue

36.7 miles

Focus on Cumberland County Animal Safety-IL Transport Stop

Chicago, IL 60176

Pet Types: cats, dogs

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Rescue

39.6 miles

God's Dogs Rescue of TX for IL Transport Stop

Rosemont, IL 60018

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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