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Puppies and dogs in De Soto, Missouri

Looking for a puppy or dog in De Soto, Missouri? Adopt a Pet can help you find a new best friend near you.

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Adopt a dog in De Soto, Missouri

These adorable dogs are available for adoption in De Soto, Missouri. To learn more about each adoptable dog, click on the "i" icon for fast facts, or their photo or name for full details.
We'll also keep you updated on Ace's adoption status with email updates.
Photo of Ace

Ace

Mutt

Male, Adult
Desoto, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Ace is so lovable and he gives so many kisses! He likes to lick and he is a very friendly dog. He loves to chase squirrels and is happy outside sometimes watching other activities. He enjoys playing with his sister Henny throughout the day, he thinks he I a lap dog and will cuddle with you and keep you warm with all the love he has to give
We'll also keep you updated on Felix's adoption status with email updates.
Photo of Felix

Felix

Anatolian Shepherd

Male, Adult
De Soto, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Felix! Your Next Adventure Buddy! Felix is a loving, laid-back dog with a curious and adventurous spirit. He enjoys going on walks, spending time with his people, and being part of everyday family life. While he can be a bit shy at first, he quickly warms up and becomes a loyal, affectionate companion. Felix is looking for a safe, loving home where he can thrive. Due to personal family circumstances, rehoming him comes from a place of care and love, with his happiness as the top priority. If you’re searching for a gentle adventure buddy and devoted friend, Felix may be the perfect fit. He also needs a fence that is 6ft tall where he can be a free spirit.
We'll also keep you updated on Henny's adoption status with email updates.
Photo of Henny

Henny

Mutt German Shorthaired Pointer

Female, Adult
Desoto, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Not good with kids, Not good with cats, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Henny likes all the attention on her and gets jealous easily. She is super lovable and will sit on a lap and give hugs. She loves to cuddle, she gets really excited when she sees other dogs, cats and her favorite are squirrels. She is strong and might try to chase ine of these animals so a tight grip and some muscle is needed to hold her back. She is very smart and learned magic tricks when she was a puppy however other command have been challenging including potty time so a little bit of love and training could make her the perfect companion although she is just perfect already.!
We'll also keep you updated on Osiris's adoption status with email updates.
Photo of Osiris

Osiris

Labrador Retriever

Male, Young
De Soto, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
We found him on our doorstep as a puppy and took him in. When we found him he was about 12 weeks old. He is currently 2 He is a smart, good watch dog and has passed an obedience class. He is housebroken and leash trained. He is good in public and loves other dogs and cats. He needs a knew home because our very big and growing family makes him anxious. We do not have a fenced yard and he needs more exercise.He does good with a small family, and would be great with elderly or single people as well. He loves frisbee, playing fetch, is trained to stay on his bed during meals and not beg. He is calm around the house and He is low shedding. He is a VERY good boy loving playful loyal friendly and obedient.
We'll also keep you updated on Inky's adoption status with email updates.
Photo of Inky

Inky

Terrier (Unknown Type, Medium) Labrador Retriever

Female, Puppy
Hillsboro, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Meet Inky, a delightful puppy brimming with energy and affection. She's known for her sweet nature and playful spirit, always ready to engage in fun activities or snuggle up for some love. Inky thrives on interaction and enjoys the company of both humans and other dogs. Her friendly demeanor makes her a fantastic companion for any family looking to add a joyful presence to their home. Adopting Inky means bringing home endless fun and unconditional love. Inky's adoption fee is $300.00 which includes 3 rounds of shots, spay, microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  January 14, 2026, 4:02 pm
We'll also keep you updated on Odin's adoption status with email updates.
Photo of Odin

Odin

American Bulldog

Male, Adult
Hillsboro, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Odin is about 70 pounds, crate and potty trained and very rarely has accidents in the house. He is super active, likes to play fetch and tug of war. He likes kids but due to his size and exuberance, he may do better with bigger kids. He also is mouthy when playing and jumps up. He thinks he is a lap dog and will definitely try to sit and lay on you. He has been to doggy daycare and gets along fine with the dogs and people there. He is anxious around new people and anytime he meets someone new he barks at them. He also gets anxious at the vet.  He is very sweet with his people but wary of others. He will do great with a family that is active and can take him on long walks. He is also very smart and trainable. He’s definitely food motivated. He can sit, stay, lay down and roll over.    Odin’s adoption fee is $100.00 which includes all shots, neuter, microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  June 11, 2025, 10:50 am

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Puppies and dogs in nearby cities

Dog shelters and rescues in De Soto, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for dogs in De Soto, Missouri. Browse these rescues and shelters below.

Here are a few organizations closest to you:

Rescue

Canines in Crisis, Inc.

De Soto, MO 63020

Pet Types: dogs

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Rescue

Paws for Consideration

2355 South Drive, Festus, MO 63028

Pet Types: cats, dogs

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Shelter

Festus Animal Control

950 N Fifth St., Festus, MO 63028

Pet Types: cats, dogs

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Rescue

We Are Not Disposable

Festus, MO 63028

Pet Types: dogs

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Rescue

Rat Terrier ResQ - MO

Festus, MO 63028

Pet Types: dogs

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Shelter

Jefferson County Animal Control

4848 State Rt 30, House Springs, MO 63028

Pet Types: cats, dogs, rabbits, small animals

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Shelter

Coalition for Animal Rescue and Education

Hillsboro, MO 63050

Pet Types: cats, dogs, horses

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Rescue

Advocates 4 Animals Pet Food Pantry

Hillsboro, MO 63050

Pet Types: dogs

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Rescue

Flawdogs Adoptions

8646 highway ee / po box 99, morse mill, MO 63066

Pet Types: dogs

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Rescue

Recycling Rover

The Rainbow Ranch, BOX 209, Morse Mill, MO 63066

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

For a comprehensive list of all shelters and rescues, try our search page. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Looking for a specific breed?

Select from the options below to view adoptable puppies and dogs in De Soto, Missouri and nearby cities.

Popular dog breeds

Affenpinscher Afghan Hound Airedale Terrier Akbash Akita Alaskan Klee Kai Alaskan Malamute American Bulldog American Cocker Spaniel American Eskimo Dog American Hairless Terrier American Pit Bull Terrier American Staffordshire Terrier Anatolian Shepherd Aussiedoodle Australian Cattle Dog Australian Kelpie Australian Shepherd Australian Terrier Basenji Basset Hound Beagle Bearded Collie Beauceron Bedlington Terrier Belgian Laekenois Belgian Malinois Belgian Shepherd Belgian Tervuren Bernedoodle Bernese Mountain Dog Bichon Frise Black Mouth Cur Black and Tan Coonhound Bloodhound Blue Lacy/Texas Lacy Bluetick Coonhound Bolognese Border Collie Border Terrier Borzoi Boston Terrier Bouvier des Flandres Boxer Boykin Spaniel Briard Brittany Brussels Griffon Bull Terrier Bullmastiff Cairn Terrier Canaan Dog Cane Corso Cardigan Welsh Corgi Carolina Dog Catahoula Leopard Dog Caucasian Shepherd Dog Cavachon Cavalier King Charles Spaniel Cavapoo Chesapeake Bay Retriever Chihuahua Chinese Crested Chinook Chiweenie Chow Chow Clumber Spaniel Cockapoo Cocker Spaniel Collie Coonhound Corgi Coton de Tulear Curly-Coated Retriever Dachshund Dalmatian Dandie Dinmont Terrier Doberman Pinscher Dogo Argentino Dogue de Bordeaux Dutch Shepherd English (Redtick) Coonhound English Bulldog English Cocker Spaniel English Setter English Shepherd English Springer Spaniel English Toy Spaniel Entlebucher Feist Field Spaniel Fila Brasileiro Finnish Lapphund Finnish Spitz Flat-Coated Retriever Fox Terrier (Smooth) Fox Terrier (Toy) Fox Terrier (Wirehaired) Foxhound French Bulldog German Pinscher German Shepherd Dog German Shorthaired Pointer German Spitz German Wirehaired Pointer Glen of Imaal Terrier Goberian Golden Retriever Goldendoodle Gordon Setter Great Dane Great Pyrenees Greater Swiss Mountain Dog Greyhound Halden Hound (Haldenstrover) Harrier Havanese Horgi Hovawart Husky Ibizan Hound Icelandic Sheepdog Irish Setter Irish Terrier Irish Water Spaniel Irish Wolfhound Italian Greyhound Italian Spinone Jack Russell Terrier Japanese Chin Jindo Kai Dog Karelian Bear Dog Keeshond Kerry Blue Terrier Kishu Komondor Kuvasz Kyi Leo Labradoodle Labrador Retriever Lakeland Terrier Lancashire Heeler Leonberger Lhasa Apso Löwchen Maltese Maltipoo Manchester Terrier Maremma Sheepdog Mastiff Miniature Bull Terrier Miniature Dachshund Miniature Pinscher Morkie Mountain Cur Munsterlander Mutt Neapolitan Mastiff Newfoundland Norfolk Terrier Norwegian Buhund Norwegian Elkhound Norwegian Lundehund Norwich Terrier Nova Scotia Duck-Tolling Retriever Old English Sheepdog Olde English Bulldogge Otterhound Papillon Parson Russell Terrier Patterdale Terrier (Fell Terrier) Pekingese Pembroke Welsh Corgi Petit Basset Griffon Vendeen Pharaoh Hound Pitsky Plott Hound Podengo Portugueso Pointer Polish Lowland Sheepdog Pomeranian Pomsky Poodle (Miniature) Poodle (Standard) Poodle (Toy or Tea Cup) Portuguese Water Dog Presa Canario Pug Puggle Puli Pumi Rat Terrier Redbone Coonhound Rhodesian Ridgeback Rottweiler Saluki Samoyed Schiller Hound Schipperke Schnauzer (Giant) Schnauzer (Miniature) Schnauzer (Standard) Schnoodle Scottie, Scottish Terrier Scottish Deerhound Sealyham Terrier Shar Pei Sheepadoodle Sheltie, Shetland Sheepdog Sheppit Shepsky Shiba Inu Shih Poo Shih Tzu Silky Terrier Skye Terrier Sloughi St. Bernard Staffordshire Bull Terrier Sussex Spaniel Swedish Vallhund Texas Heeler Thai Ridgeback Tibetan Mastiff Tibetan Spaniel Tibetan Terrier Tosa Inu Treeing Walker Coonhound Vizsla Weimaraner Welsh Springer Spaniel Welsh Terrier Westie, West Highland White Terrier Wheaten Terrier Whippet Wirehaired Pointing Griffon Xoloitzcuintle/Mexican Hairless Yorkie Poo Yorkie, Yorkshire Terrier