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Puppies and dogs in De Soto, Missouri

Looking for a puppy or dog in De Soto, Missouri? Adopt a Pet can help you find a new best friend near you.

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Adopt a dog in De Soto, Missouri

These adorable dogs are available for adoption in De Soto, Missouri. To learn more about each adoptable dog, click on the "i" icon for fast facts, or their photo or name for full details.
Photo of Bear

Bear

Beagle Terrier (Unknown Type, Medium)

Female, Adult
Festus, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats, House-trained, Spayed or Neutered,
Story
11 year old beagle/pit mix. Very sweet old lady. Loves to cuddle and get belly rubs from humans. Loves to give kisses. Not friendly around other small animals. Skiddish, scared of thunderstorms and fireworks.
Photo of Nala

Nala

Labrador Retriever Terrier (Unknown Type, Medium)

Female, Adult
Festus, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
9 year old female. Fixed. Still very much hyper and happy dog. Loves to rough house and get belly rubs. Loves food and snacks. Needs a good home that will get her energy out.
Photo of Nelson

Nelson

Pit Bull Terrier

Male, Puppy
Hillsboro, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Meet Nelson, a delightful puppy brimming with joy and love. Nelson has become known for his sweet, friendly nature. He's the first to greet visitors with a wagging tail, eager for a cuddle or a playful game. Nelson's affectionate demeanor makes him a perfect companion for any family looking for a furry friend to bring happiness and energy into their home. Adopting Nelson means gaining a loyal friend who will always be there to brighten your days with unconditional love and playful antics. a Nelson’s adoption fee is $300.00 which includes 3 rounds of shots, neuter, microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  June 5, 2026, 7:31 am
Photo of Brooks

Brooks

Pit Bull Terrier

Male, Puppy
Hillsboro, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Meet Brooks, a delightful puppy with a heart full of joy. This sweet, friendly, and cuddly little guy loves to play and share affection with everyone he meets. His playful antics are sure to bring a smile to your face, and his eagerness for cuddles will warm your heart. Brooks is looking for a forever home where he can share his boundless love and playful spirit. Adopting Brooks means gaining a loyal friend who will fill your days with laughter and companionship. Brooks’s adoption fee is $300.00 which includes 3 rounds of shots,      , microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  June 5, 2026, 7:31 am
Photo of Frankie

Frankie

Pit Bull Terrier American Pit Bull Terrier

Female, Puppy
Hillsboro, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Frankie, 5 months old •Chocolate brunette  •Looking for her perfect match Hi, I'm Frankie — a 5-month-old Pitbull mix with gorgeous chocolate brown coloring, cute white markings, and a personality that's impossible to ignore. I'm currently accepting applications for my forever family... serious inquiries only.  A little about me: *Fully vaccinated & spayed *Fully potty trained *Fully crate trained *Very smart & a fast learner * Knows basic commands *Loves kids, dogs, car rides, and cuddles I'm playful, affectionate, and always ready for an adventure, but I also believe naps on the couch are an important part of a balanced lifestyle. I love making friends and would thrive in a home where I have another dog to wrestle, zoom, and play with. My perfect match? A family who wants a loyal best friend with brains, beauty, and endless love to give. Bonus points if you already have a playful pup looking for their new BFF. If you think we could be the perfect match fill out an application today! Meet and greets available - because every great love story deserves a first date. Frankie's adoption fee is $195.00 which includes 3 rounds of shots, spay, microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  June 5, 2026, 7:31 am
Photo of Luca

Luca

Labrador Retriever Husky

Male, Puppy
Hillsboro, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Meet Luca, the delightful puppy whose days are filled with playful antics and cuddly moments. Luca is known for his sweet nature and his love for engaging in fun games. He's always ready to share a gentle nuzzle or a joyful play session with anyone who visits. Luca's infectious enthusiasm and loving personality make him the perfect companion for any home looking for a burst of joy and affection. Adopting Luca means bringing home endless love and playful adventures every day. Luca's adoption fee is $300.00 which includes 3 rounds of shots, neuter, microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  June 5, 2026, 7:31 am

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Use the search tool below to browse adoptable puppies and adult dogs in De Soto, Missouri.

Puppies and dogs in nearby cities

Dog shelters and rescues in De Soto, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for dogs in De Soto, Missouri. Browse these rescues and shelters below.

Here are a few organizations closest to you:

Rescue

Canines in Crisis, Inc.

De Soto, MO 63020

Pet Types: dogs

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Rescue

Paws for Consideration

2355 South Drive, Festus, MO 63028

Pet Types: cats, dogs

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Rescue

Rat Terrier ResQ - MO

Festus, MO 63028

Pet Types: dogs

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Rescue

We Are Not Disposable

Festus, MO 63028

Pet Types: dogs

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Shelter

Jefferson County Animal Control

4848 State Rt 30, House Springs, MO 63028

Pet Types: cats, dogs, rabbits, small animals

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Rescue

Advocates 4 Animals Pet Food Pantry

Hillsboro, MO 63050

Pet Types: dogs

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Shelter

Coalition for Animal Rescue and Education

Hillsboro, MO 63050

Pet Types: cats, dogs, horses

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Rescue

Recycling Rover

The Rainbow Ranch, BOX 209, Morse Mill, MO 63066

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

Flawdogs Adoptions

8646 highway ee / po box 99, morse mill, MO 63066

Pet Types: dogs

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Shelter

City of Pevely Animal Shelter

501 Dunklin Industrial Dr, Pevely, MO 63070

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

For a comprehensive list of all shelters and rescues, try our search page. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Looking for a specific breed?

Select from the options below to view adoptable puppies and dogs in De Soto, Missouri and nearby cities.

Popular dog breeds

Affenpinscher Afghan Hound Airedale Terrier Akbash Akita Alaskan Klee Kai Alaskan Malamute American Bulldog American Cocker Spaniel American Eskimo Dog American Hairless Terrier American Pit Bull Terrier American Staffordshire Terrier Anatolian Shepherd Aussiedoodle Australian Cattle Dog Australian Kelpie Australian Shepherd Australian Terrier Basenji Basset Hound Beagle Bearded Collie Beauceron Bedlington Terrier Belgian Laekenois Belgian Malinois Belgian Shepherd Belgian Tervuren Bernedoodle Bernese Mountain Dog Bichon Frise Black Mouth Cur Black and Tan Coonhound Bloodhound Blue Lacy/Texas Lacy Bluetick Coonhound Bolognese Border Collie Border Terrier Borzoi Boston Terrier Bouvier des Flandres Boxer Boykin Spaniel Briard Brittany Brussels Griffon Bull Terrier Bullmastiff Cairn Terrier Canaan Dog Cane Corso Cardigan Welsh Corgi Carolina Dog Catahoula Leopard Dog Caucasian Shepherd Dog Cavachon Cavalier King Charles Spaniel Cavapoo Chesapeake Bay Retriever Chihuahua Chinese Crested Chinook Chiweenie Chow Chow Clumber Spaniel Cockapoo Cocker Spaniel Collie Coonhound Corgi Coton de Tulear Curly-Coated Retriever Dachshund Dalmatian Dandie Dinmont Terrier Doberman Pinscher Dogo Argentino Dogue de Bordeaux Dutch Shepherd English (Redtick) Coonhound English Bulldog English Cocker Spaniel English Setter English Shepherd English Springer Spaniel English Toy Spaniel Entlebucher Feist Field Spaniel Fila Brasileiro Finnish Lapphund Finnish Spitz Flat-Coated Retriever Fox Terrier (Smooth) Fox Terrier (Toy) Fox Terrier (Wirehaired) Foxhound French Bulldog German Pinscher German Shepherd Dog German Shorthaired Pointer German Spitz German Wirehaired Pointer Glen of Imaal Terrier Goberian Golden Retriever Goldendoodle Gordon Setter Great Dane Great Pyrenees Greater Swiss Mountain Dog Greyhound Halden Hound (Haldenstrover) Harrier Havanese Horgi Hovawart Husky Ibizan Hound Icelandic Sheepdog Irish Setter Irish Terrier Irish Water Spaniel Irish Wolfhound Italian Greyhound Italian Spinone Jack Russell Terrier Japanese Chin Jindo Kai Dog Karelian Bear Dog Keeshond Kerry Blue Terrier Kishu Komondor Kuvasz Kyi Leo Labradoodle Labrador Retriever Lakeland Terrier Lancashire Heeler Leonberger Lhasa Apso Löwchen Maltese Maltipoo Manchester Terrier Maremma Sheepdog Mastiff Miniature Bull Terrier Miniature Dachshund Miniature Pinscher Morkie Mountain Cur Munsterlander Mutt Neapolitan Mastiff Newfoundland Norfolk Terrier Norwegian Buhund Norwegian Elkhound Norwegian Lundehund Norwich Terrier Nova Scotia Duck-Tolling Retriever Old English Sheepdog Olde English Bulldogge Otterhound Papillon Parson Russell Terrier Patterdale Terrier (Fell Terrier) Pekingese Pembroke Welsh Corgi Petit Basset Griffon Vendeen Pharaoh Hound Pitsky Plott Hound Podengo Portugueso Pointer Polish Lowland Sheepdog Pomeranian Pomsky Poodle (Miniature) Poodle (Standard) Poodle (Toy or Tea Cup) Portuguese Water Dog Presa Canario Pug Puggle Puli Pumi Rat Terrier Redbone Coonhound Rhodesian Ridgeback Rottweiler Saluki Samoyed Schiller Hound Schipperke Schnauzer (Giant) Schnauzer (Miniature) Schnauzer (Standard) Schnoodle Scottie, Scottish Terrier Scottish Deerhound Sealyham Terrier Shar Pei Sheepadoodle Sheltie, Shetland Sheepdog Sheppit Shepsky Shiba Inu Shih Poo Shih Tzu Silky Terrier Skye Terrier Sloughi St. Bernard Staffordshire Bull Terrier Sussex Spaniel Swedish Vallhund Texas Heeler Thai Ridgeback Tibetan Mastiff Tibetan Spaniel Tibetan Terrier Tosa Inu Treeing Walker Coonhound Vizsla Weimaraner Welsh Springer Spaniel Welsh Terrier Westie, West Highland White Terrier Wheaten Terrier Whippet Wirehaired Pointing Griffon Xoloitzcuintle/Mexican Hairless Yorkie Poo Yorkie, Yorkshire Terrier