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Puppies and dogs in De Soto, Missouri

Looking for a puppy or dog in De Soto, Missouri? Adopt a Pet can help you find a new best friend near you.

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Adopt a dog in De Soto, Missouri

These adorable dogs are available for adoption in De Soto, Missouri. To learn more about each adoptable dog, click on the "i" icon for fast facts, or their photo or name for full details.
Photo of Pixie

Pixie

Pitsky Pitsky

Female, Young
De Soto, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
1.5 years old Good dog She has no issues Just can't keep her, I am relocating
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Photo of Athena

Athena

American Pit Bull Terrier

Female, Young
De Soto, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
She came from a litter of 6 puppies. She should have just turned 1 year old, she needs someone that has a lot of time to work with her. She is an extremely high energy dog
Photo of Mick

Mick

Australian Shepherd Shepherd (Unknown Type)

Male, Young
Blackwell, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Looking for a Loving Home for a Good Boy ❤️🐾This is a hard post to make because he really does want to be a good boy. ❤️He has so much love to give! He absolutely loves to play, gets excited for treats, and walks beautifully on a leash. He’s a fun, sweet boy who just needs the right environment to thrive.Unfortunately, despite our best efforts, he just can’t resist chasing our pigs and chickens. Farm life simply isn’t the right fit for him, and it’s not fair to him or our other animals to keep putting him in that situation.What he needs is a home with a big, securely fenced yard, plenty of playtime, and humans who will love him as much as he deserves. A home without livestock or poultry would be ideal.He’s not a bad dog. He’s just a good boy who hasn’t found the right place to be his best self. 🥹We’re not looking to just give him away. We’re looking for the right family who will give him a safe, happy, loving forever home.
Photo of Lumi

Lumi

Labrador Retriever

Female, Young
Hillsboro, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Meet One of Momma Bella’s Adorable Babies! Big personalities, endless puppy kisses, and enough cuteness to steal your heart! ❤️ These little bundles of joy love playing with toys outside, exploring their world, and showing off their silly personalities. When playtime is over, they’re perfectly happy curling up in your lap for snuggles or settling into their own space for a puppy nap. Age: 7 weeks old as of October 20 Mom: The amazing Bella Potty Training: A work in progress! ❤️ Ready for Adoption: After November 4 These babies are full of love, personality, and puppy mischief! Can’t wait until November 4? Consider fostering one (or two!) while they get ready for their forever homes. It’s a wonderful way to get extra puppy cuddles while helping them grow! Ready to fall in love? Apply to adopt or message us about fostering!   Lumi’s    adoption fee is $300.00 which includes 3 rounds of shots,      , microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  November 4, 2026, 1:26 pm
Photo of Bella M

Bella M

Labrador Retriever

Female, Adult
Hillsboro, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Behind NINE beautiful, happy, and incredibly well-cared-for puppies is one AMAZING momma… meet Bella! ❤️ Even at 7 weeks old, her babies still have her wrapped around their tiny paws! Bella continues to help her foster mom with cleanup duty, loves going outside to play with her babies, and STILL lets them nurse at the milk bar… even though it closed for business weeks ago! This sweet girl has given her babies everything she has, and soon it will be HER turn to be spoiled, loved, and cared for by a forever family. ❤️ Who’s ready to give this amazing momma the happily ever after she deserves? Bella’s adoption fee is $200.00 which includes all shots, spay, microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  November 4, 2026, 1:26 pm
Photo of Moxie

Moxie

Labrador Retriever

Female, Young
Hillsboro, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Meet One of Momma Bella’s Adorable Babies! Big personalities, endless puppy kisses, and enough cuteness to steal your heart! ❤️ These little bundles of joy love playing with toys outside, exploring their world, and showing off their silly personalities. When playtime is over, they’re perfectly happy curling up in your lap for snuggles or settling into their own space for a puppy nap. Age: 7 weeks old as of October 20 Mom: The amazing Bella Potty Training: A work in progress! ❤️ Ready for Adoption: After November 4 These babies are full of love, personality, and puppy mischief! Can’t wait until November 4? Consider fostering one (or two!) while they get ready for their forever homes. It’s a wonderful way to get extra puppy cuddles while helping them grow! Ready to fall in love? Apply to adopt or message us about fostering! Moxie’s  adoption fee is $350.00 which includes 3 rounds of shots,      , microchip and 1 month of heartworm preventative. If you are interested, please complete the Adoption Application on our website at a4apetpantry.org Disclaimer: Visual breed identification in dogs is unreliable, so for most of our dogs, we are only guessing at breed mix.  November 4, 2026, 1:26 pm

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Puppies and dogs in nearby cities

Dog shelters and rescues in De Soto, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for dogs in De Soto, Missouri. Browse these rescues and shelters below.

Here are a few organizations closest to you:

Rescue

Canines in Crisis, Inc.

De Soto, MO 63020

Pet Types: dogs

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Rescue

Rat Terrier ResQ - MO

Festus, MO 63028

Pet Types: dogs

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Shelter

Jefferson County Animal Control

4848 State Rt 30, House Springs, MO 63028

Pet Types: cats, dogs, rabbits, small animals

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Rescue

We Are Not Disposable

Festus, MO 63028

Pet Types: dogs

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Rescue

Paws for Consideration

2355 South Drive, Festus, MO 63028

Pet Types: cats, dogs

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Rescue

Advocates 4 Animals Pet Food Pantry

Hillsboro, MO 63050

Pet Types: dogs

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Shelter

Coalition for Animal Rescue and Education

Hillsboro, MO 63050

Pet Types: cats, dogs, horses

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Rescue

Flawdogs Adoptions

8646 highway ee / po box 99, morse mill, MO 63066

Pet Types: dogs

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Rescue

Recycling Rover

The Rainbow Ranch, BOX 209, Morse Mill, MO 63066

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

Harter's Hospice and Puppy Rescue

Pevely, MO 63070

Pet Types: dogs

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Looking for a specific shelter or rescue?

For a comprehensive list of all shelters and rescues, try our search page. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Looking for a specific breed?

Select from the options below to view adoptable puppies and dogs in De Soto, Missouri and nearby cities.

Popular dog breeds

Affenpinscher Afghan Hound Airedale Terrier Akbash Akita Alaskan Klee Kai Alaskan Malamute American Bulldog American Cocker Spaniel American Eskimo Dog American Hairless Terrier American Pit Bull Terrier American Staffordshire Terrier Anatolian Shepherd Aussiedoodle Australian Cattle Dog Australian Kelpie Australian Shepherd Australian Terrier Basenji Basset Hound Beagle Bearded Collie Beauceron Bedlington Terrier Belgian Laekenois Belgian Malinois Belgian Shepherd Belgian Tervuren Bernedoodle Bernese Mountain Dog Bichon Frise Black Mouth Cur Black and Tan Coonhound Bloodhound Blue Lacy/Texas Lacy Bluetick Coonhound Bolognese Border Collie Border Terrier Borzoi Boston Terrier Bouvier des Flandres Boxer Boykin Spaniel Briard Brittany Brussels Griffon Bull Terrier Bullmastiff Cairn Terrier Canaan Dog Cane Corso Cardigan Welsh Corgi Carolina Dog Catahoula Leopard Dog Caucasian Shepherd Dog Cavachon Cavalier King Charles Spaniel Cavapoo Chesapeake Bay Retriever Chihuahua Chinese Crested Chinook Chiweenie Chow Chow Clumber Spaniel Cockapoo Cocker Spaniel Collie Coonhound Corgi Coton de Tulear Curly-Coated Retriever Dachshund Dalmatian Dandie Dinmont Terrier Doberman Pinscher Dogo Argentino Dogue de Bordeaux Dutch Shepherd English (Redtick) Coonhound English Bulldog English Cocker Spaniel English Setter English Shepherd English Springer Spaniel English Toy Spaniel Entlebucher Feist Field Spaniel Fila Brasileiro Finnish Lapphund Finnish Spitz Flat-Coated Retriever Fox Terrier (Smooth) Fox Terrier (Toy) Fox Terrier (Wirehaired) Foxhound French Bulldog German Pinscher German Shepherd Dog German Shorthaired Pointer German Spitz German Wirehaired Pointer Glen of Imaal Terrier Goberian Golden Retriever Goldendoodle Gordon Setter Great Dane Great Pyrenees Greater Swiss Mountain Dog Greyhound Halden Hound (Haldenstrover) Harrier Havanese Horgi Hovawart Husky Ibizan Hound Icelandic Sheepdog Irish Setter Irish Terrier Irish Water Spaniel Irish Wolfhound Italian Greyhound Italian Spinone Jack Russell Terrier Japanese Chin Jindo Kai Dog Karelian Bear Dog Keeshond Kerry Blue Terrier Kishu Komondor Kuvasz Kyi Leo Labradoodle Labrador Retriever Lakeland Terrier Lancashire Heeler Leonberger Lhasa Apso Löwchen Maltese Maltipoo Manchester Terrier Maremma Sheepdog Mastiff Miniature Bull Terrier Miniature Dachshund Miniature Pinscher Morkie Mountain Cur Munsterlander Mutt Neapolitan Mastiff Newfoundland Norfolk Terrier Norwegian Buhund Norwegian Elkhound Norwegian Lundehund Norwich Terrier Nova Scotia Duck-Tolling Retriever Old English Sheepdog Olde English Bulldogge Otterhound Papillon Parson Russell Terrier Patterdale Terrier (Fell Terrier) Pekingese Pembroke Welsh Corgi Petit Basset Griffon Vendeen Pharaoh Hound Pitsky Plott Hound Podengo Portugueso Pointer Polish Lowland Sheepdog Pomeranian Pomsky Poodle (Miniature) Poodle (Standard) Poodle (Toy or Tea Cup) Portuguese Water Dog Presa Canario Pug Puggle Puli Pumi Rat Terrier Redbone Coonhound Rhodesian Ridgeback Rottweiler Saluki Samoyed Schiller Hound Schipperke Schnauzer (Giant) Schnauzer (Miniature) Schnauzer (Standard) Schnoodle Scottie, Scottish Terrier Scottish Deerhound Sealyham Terrier Shar Pei Sheepadoodle Sheltie, Shetland Sheepdog Sheppit Shepsky Shiba Inu Shih Poo Shih Tzu Silky Terrier Skye Terrier Sloughi St. Bernard Staffordshire Bull Terrier Sussex Spaniel Swedish Vallhund Texas Heeler Thai Ridgeback Tibetan Mastiff Tibetan Spaniel Tibetan Terrier Tosa Inu Treeing Walker Coonhound Vizsla Weimaraner Welsh Springer Spaniel Welsh Terrier Westie, West Highland White Terrier Wheaten Terrier Whippet Wirehaired Pointing Griffon Xoloitzcuintle/Mexican Hairless Yorkie Poo Yorkie, Yorkshire Terrier